Oxipurinol
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Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Oxypurinol inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the blood and urine. Oxypurinol also facilitates the incorporation of hypoxanthine and xanthine into DNA and RNA, resulting in further reductions of serum uric acid concentrations.
用于高尿酸血症，对别嘌醇耐受不良的痛风发作有效。
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
