Overview
An essential amino acid that is required for the production of histamine.
Indication
The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2024/10/26 | Phase 2 | Not yet recruiting | Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba | ||
2023/12/14 | Phase 4 | Withdrawn | |||
2021/02/21 | Phase 2 | Withdrawn | |||
2015/12/01 | Phase 2 | UNKNOWN | National Cardiovascular Center Harapan Kita Hospital Indonesia |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Baxter Healthcare Corporation | 0338-0184 | INTRAVENOUS | 384 mg in 100 mL | 4/13/2021 | |
| Baxter Healthcare Company | 0338-0210 | INTRAVENOUS | 384 mg in 100 mL | 9/21/2020 | |
| Baxter Healthcare Corporation | 0338-0210 | INTRAVENOUS | 384 mg in 100 mL | 9/21/2020 | |
| Baxter Healthcare Corporation | 0338-1089 | INTRAVENOUS | 204 mg in 100 mL | 4/13/2021 | |
| Baxter Healthcare Corporation | 0338-1099 | INTRAVENOUS | 240 mg in 100 mL | 4/13/2021 | |
| ICU Medical Inc. | 0990-7171 | INTRAVENOUS | 450 mg in 100 mL | 5/4/2022 | |
| Baxter Healthcare Corporation | 0338-0194 | INTRAVENOUS | 384 mg in 100 mL | 4/13/2021 | |
| Baxter Healthcare Company | 0338-1147 | INTRAVENOUS | 240 mg in 100 mL | 9/21/2020 | |
| Baxter Healthcare Corporation | 0338-1147 | INTRAVENOUS | 240 mg in 100 mL | 9/21/2020 | |
| Baxter Healthcare Company | 0338-1142 | INTRAVENOUS | 132 mg in 100 mL | 9/21/2020 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| TROPHAMINE INJECTION 10% | SIN07846P | INJECTION | 0.48 g/100 ml | 9/12/1994 | |
| SYNTHAMIN 17 WITHOUT ELECTROLYTES 10% AMINO ACID INTRAVENOUS INFUSION | SIN09992P | INJECTION | 4.80 g/l | 9/15/1998 | |
| AMINOPLASMAL-15% INFUSION | SIN08352P | INJECTION | 5.25 g/l | 9/14/1995 | |
| AMINOPLASMAL B.BRAUN 10% E SOLUTION FOR INFUSION | SIN15411P | INFUSION, SOLUTION | 3.00g/1000ml | 1/23/2018 | |
| AMINOVEN SOLUTION FOR INFUSION 15% | SIN16337P | INFUSION, SOLUTION | 7.3g/L | 9/30/2021 | |
| KABIVEN EMULSION FOR INFUSION | SIN11657P | INJECTION | 2 g/1000 ml | 9/4/2001 | |
| SmofKabiven Peripheral Emulsion for Infusion | SIN14287P | INJECTION, EMULSION | 3.0g /1000ml | 1/8/2013 | |
| PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION | SIN10252P | INJECTION | 3.8 g/l | 9/23/1998 | |
| AMINOVEN SOLUTION FOR INFUSION 5% | SIN11682P | INJECTION | 1.500g/1000 ml | 9/25/2001 | |
| NUTRIFLEX® OMEGA SPECIAL EMULSION FOR INFUSION | SIN15469P | INJECTION, EMULSION | 2.368g/1000ml | 4/23/2018 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| VAMINOLACT I.V. SOLUTION | N/A | N/A | N/A | 10/14/1992 | |
| OLIMEL N9E EMULSION FOR INFUSION | N/A | N/A | N/A | 10/24/2013 | |
| SMOFKABIVEN EMULSION FOR INFUSION | N/A | N/A | N/A | 5/26/2011 | |
| PAN-AMIN G SOLUTION FOR INFUSION 500ML | N/A | otsuka pharmaceutical (h.k.) limited | N/A | N/A | 4/5/2012 |
| PAN-AMIN G INJ | N/A | N/A | N/A | 5/17/1979 | |
| NUTRINEAL PD4 SOLUTION | N/A | N/A | N/A | 9/9/1999 | |
| NUTRINEAL PD-4 W/1.1% AA PERITONEAL DIAL SOLN | N/A | N/A | N/A | 12/31/2003 | |
| LA-FLAMING INJ. | N/A | N/A | N/A | 1/28/2010 | |
| NUTRIFLEX OMEGA PLUS EMULSION FOR INFUSION | N/A | N/A | N/A | 1/11/2012 | |
| AMINOGEN-S SOLUTION FOR INFUSION | N/A | wings pharmaceutical ltd | N/A | N/A | 8/15/2013 |
TGA Drug Approvals
Help Us Improve
Your feedback helps us provide better drug information and insights.