Dapsone

Generic Name
Dapsone
Brand Names
Aczone
Drug Type
Small Molecule
Chemical Formula
C12H12N2O2S
CAS Number
80-08-0
Unique Ingredient Identifier
8W5C518302
Background

A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Phar...

Indication

For the treatment and management of leprosy and dermatitis herpetiformis.

Associated Conditions
Acne Vulgaris, Bullous Systemic Lupus Erythematosus, Bullous dermatitis herpetiformis, Hansen's Disease, Pemphigus Vulgaris (PV), Relapsing Polychondritis, Mild Pneumocystis pneumonia, Mild Toxoplasma gondii encephalitis, Moderate Pneumocystis pneumonia, Moderate Toxoplasma gondii encephalitis, Refractory Idiopathic thrombocytopenic purpura
Associated Therapies
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