Dapsone
- Generic Name
- Dapsone
- Brand Names
- Aczone
- Drug Type
- Small Molecule
- Chemical Formula
- C12H12N2O2S
- CAS Number
- 80-08-0
- Unique Ingredient Identifier
- 8W5C518302
- Background
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Phar...
- Indication
For the treatment and management of leprosy and dermatitis herpetiformis.
- Associated Conditions
- Acne Vulgaris, Bullous Systemic Lupus Erythematosus, Bullous dermatitis herpetiformis, Hansen's Disease, Pemphigus Vulgaris (PV), Relapsing Polychondritis, Mild Pneumocystis pneumonia, Mild Toxoplasma gondii encephalitis, Moderate Pneumocystis pneumonia, Moderate Toxoplasma gondii encephalitis, Refractory Idiopathic thrombocytopenic purpura
- Associated Therapies
- -
Diffuse Fibrotic Lung Disease
Phase 2
Completed
- Conditions
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