Nicotine

MD Anderson's Research Highlights include: Smoking cessation meds safe for depression; definitive radiotherapy effective for metastatic thyroid cancers; targeting signaling pathways may overcome pancreatic cancer treatment resistance; ctDNA analysis reveals prognostic insights for appendix cancer; TP53 aberrations impact myeloid leukemia treatment response and survival.

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New research shows nearly half of 18- to 24-year-olds quit vaping after a quit program with phone-based coaching, a health app, and nicotine replacement therapy. The study highlights the effectiveness of phone-based support for young adult vapers.

Benjels, co-founder of pump.science, discusses DeSci innovation, tokenizing drug IP, and plans to launch 20 new experimental tokens around Christmas, emphasizing the potential of DeSci to fund medical research and longevity technologies.

Smokers quit more often when offered automatic support in an opt-out program, with 22% quitting vs. 16% in an opt-in program, according to a study in JAMA Network Open. Researchers found opt-out treatment effective regardless of initial desire to quit.

E-cigarettes, often used to quit smoking, can lead to addiction; 60% of vapers want to quit. FDA hasn't approved them as cessation tools, but some medications for smoking may help. A new drug, cytisinicline, shows promise in trials and may be approved by 2027. Nicotine pouches like Zyn are used to wean off vaping, but caution is advised.

Qnovia received FDA clearance for RespiRX nicotine inhaler clinical trial as smoking replacement therapy, planning UK pivotal trial in 2025 to support MAA submission by 2026. RespiRX aims to offer a more effective alternative to existing nicotine replacement therapies.

Daily cigarette smokers may qualify for a UAB research study involving online screening, 8 contacts over 6 months, and trying varenicline or nicotine patches/lozenges. Compensation available. More info at https://redcap.musc.edu/surveys/?s=8JWFT9XFY3FYR7Y3.

Fewer U.S. middle and high school students are using e-cigarettes, with 6% reporting use, down from 7.7% last year. High school students led the decline, while nicotine pouches are growing in popularity among youth.

The Smoking Cessation Hotline offers 24/7 support in multiple languages, including counseling, medication info, and referrals to free services. Youth Quitline targets under-25s with tailored cessation support. Effective quitting combines counseling and medication, available via mail with follow-up. Various centers provide free cessation services, including Chinese medicine and acupuncture. The Workplace Smoking Cessation Programme promotes smoke-free environments with comprehensive support.