Nicotine
- Generic Name
- Nicotine
- Brand Names
- Habitrol, Nicoderm C-Q, Nicorelief, Nicorette, Nicotrol
- Drug Type
- Small Molecule
- Chemical Formula
- C10H14N2
- CAS Number
- 54-11-5
- Unique Ingredient Identifier
- 6M3C89ZY6R
- Background
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
- Indication
For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
- Associated Conditions
- Withdrawal Nicotine
- Associated Therapies
- Smoking cessation therapy
Computer-Assisted Scheduling of Nicotine Inhaler Use in Participants Who Plan to Stop Smoking
- Conditions
- First Posted Date
- 2004-03-19
- Last Posted Date
- 2013-05-15
- Lead Sponsor
- Personal Improvement Computer Systems
- Registration Number
- NCT00021138
- Locations
- 🇺🇸
Personal Improvement Computer Systems, Incorporated, Reston, Virginia, United States
Comparison of Nicotine Inhaler and/or Bupropion in Helping People to Stop Smoking and Prevent the Recurrence of Smoking
- Conditions
- Interventions
- First Posted Date
- 2004-02-06
- Last Posted Date
- 2016-07-13
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Target Recruit Count
- 1708
- Registration Number
- NCT00033592
- Locations
- 🇺🇸
Cancer Center of Kansas - Wichita, Wichita, Kansas, United States
🇺🇸CCOP - Carle Cancer Center, Urbana, Illinois, United States
🇺🇸CCOP - Scottsdale Oncology Program, Scottsdale, Arizona, United States
Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage Cancer
- First Posted Date
- 2003-08-11
- Last Posted Date
- 2023-06-15
- Lead Sponsor
- Eastern Cooperative Oncology Group
- Target Recruit Count
- 434
- Registration Number
- NCT00002520
- Locations
- 🇺🇸
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Tobacco Cessation in Postmenopausal Women (Part II) - 2
- Conditions
- First Posted Date
- 2003-05-22
- Last Posted Date
- 2015-12-02
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 1
- Registration Number
- NCT00061074
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery
- Conditions
- Interventions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-03-11
- Lead Sponsor
- SWOG Cancer Research Network
- Target Recruit Count
- 10
- Registration Number
- NCT00032084
- Locations
- 🇺🇸
USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States
🇺🇸Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center, Los Angeles, California, United States
🇺🇸Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States
5HT3 Antagonism and Auditory Gating in Schizophrenia
- Conditions
- First Posted Date
- 2001-07-05
- Last Posted Date
- 2009-01-21
- Lead Sponsor
- US Department of Veterans Affairs
- Registration Number
- NCT00018850
- Locations
- 🇺🇸
VAMC, Denver, Colorado, United States
Behavioral Economics of Human Drug Self-Administration
- Conditions
- First Posted Date
- 2000-06-02
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Registration Number
- NCT00005765
- Locations
- 🇺🇸
University of Vermont, Burlington, Vermont, United States
Drug Development Updates
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