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Paclitaxel docosahexaenoic acid

Generic Name
Paclitaxel docosahexaenoic acid
Drug Type
Small Molecule
Chemical Formula
C69H81NO15
CAS Number
199796-52-6
Unique Ingredient Identifier
OJE5810C4F
Background

A combination of docosahexaenoic Acid (a natural fatty acid) and paclitaxel (an anticancer drug) being studied in the treatment of cancer. It is a type of mitotic inhibitor.

Indication

Investigated for use/treatment in breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer.

Taxoprexin® Treatment for Advanced Primary Cancers of the Liver

Phase 2
Terminated
Conditions
Cancer of the Liver
Interventions
First Posted Date
2007-01-17
Last Posted Date
2017-05-10
Lead Sponsor
American Regent, Inc.
Target Recruit Count
13
Registration Number
NCT00422877
Locations
🇺🇸

University of Texas, MD Anderson Cancer Center, Houston, Texas, United States

Taxoprexin Treatment for Advanced Skin Melanoma

Phase 2
Completed
Conditions
Metastatic Melanoma
First Posted Date
2005-11-07
Last Posted Date
2018-01-24
Lead Sponsor
American Regent, Inc.
Target Recruit Count
30
Registration Number
NCT00249262

Taxoprexin® Treatment for Advanced Eye Melanoma

Phase 2
Completed
Conditions
Metastatic Melanoma
First Posted Date
2005-10-27
Last Posted Date
2018-01-24
Lead Sponsor
American Regent, Inc.
Target Recruit Count
30
Registration Number
NCT00244816
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

Taxoprexin Plus Carboplatin Treatment for Advanced Lung Cancer

Phase 3
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2005-10-25
Last Posted Date
2018-01-26
Lead Sponsor
American Regent, Inc.
Target Recruit Count
519
Registration Number
NCT00243867
Locations
🇺🇸

US Oncology, Dallas, Texas, United States

DHA-Paclitaxel in Treating Patients With Metastatic Colorectal Cancer

Phase 2
Conditions
Colorectal Cancer
First Posted Date
2004-01-15
Last Posted Date
2008-07-24
Lead Sponsor
Theradex
Registration Number
NCT00024401
Locations
🇺🇸

Arizona Oncology Associates, Tucson, Arizona, United States

🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

Veterans Affairs Medical Center - East Orange, East Orange, New Jersey, United States

and more 3 locations

Chemotherapy in Treating Patients With Metastatic Kidney Cancer

Phase 2
Conditions
Kidney Cancer
First Posted Date
2004-01-14
Last Posted Date
2008-07-24
Lead Sponsor
Theradex
Registration Number
NCT00024388
Locations
🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

Louisiana State University Health Sciences Center - Shreveport, Shreveport, Louisiana, United States

🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

and more 4 locations

DHA-Paclitaxel in Treating Patients With Metastatic Pancreatic Cancer

Phase 2
Conditions
Pancreatic Cancer
First Posted Date
2003-01-27
Last Posted Date
2009-02-18
Lead Sponsor
Theradex
Registration Number
NCT00024375
Locations
🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

Kimmel Cancer Center of Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Virginia Mason Medical Center, Seattle, Washington, United States

and more 6 locations

DHA-Paclitaxel in Treating Patients With Metastatic Prostate Cancer

Phase 2
Conditions
Prostate Cancer
First Posted Date
2003-01-27
Last Posted Date
2008-07-24
Lead Sponsor
Theradex
Registration Number
NCT00024414
Locations
🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

Kimmel Cancer Center of Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Alta Bates Comprehensive Cancer Center, Berkeley, California, United States

and more 5 locations
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