MedPath

Porfimer Sodium

Generic Name
Porfimer Sodium
Brand Names
Photofrin
Drug Type
Small Molecule
CAS Number
87806-31-3
Unique Ingredient Identifier
Y3834SIK5F

Overview

The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in the United States.

Background

The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in the United States.

Indication

临床上用于对不能用手术及其他根治疗法的肺、子宫颈癌或需非手术治疗的患者,在内镜下能观察到病灶的全貌、可能进行激光照射的下列疾病:早期肺癌(0期或Ⅰ期)、浅表性食管癌、浅表性早期胃癌、宫颈癌初期及发育异常。

Associated Conditions

  • Barrett's Esophagus
  • Esophageal Cancer
  • Completely obstructive Non-small cell lung cancer
  • Microinvasive endobrachial Non-small cell lung cancer
  • Partially obstructive Non-small cell lung cancer

FDA Approved Products

Photofrin
Manufacturer:Pinnacle Biologics, Inc.
Route:INTRAVENOUS
Strength:75 mg in 31.8 mL
Approved: 2023/08/15
NDC:76128-155

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath