Lumefantrine
- Generic Name
- Lumefantrine
- Brand Names
- Coartem
- Drug Type
- Small Molecule
- Chemical Formula
- C30H32Cl3NO
- CAS Number
- 82186-77-4
- Unique Ingredient Identifier
- F38R0JR742
- Background
Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including infe...
- Indication
Lumefantrine and artemether combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the Plasmodium species has not been identified. Indicated for use in adults and children greater than 5 k...
- Associated Conditions
- Uncomplicated Malaria caused by Plasmodium falciparum
- Associated Therapies
- -
Zambia Integrated Management of Malaria and Pneumonia Study
- Conditions
- Interventions
- First Posted Date
- 2007-08-08
- Last Posted Date
- 2010-07-20
- Lead Sponsor
- Boston University
- Target Recruit Count
- 3125
- Registration Number
- NCT00513500
- Locations
- 🇿🇲
Chikankata Health Services, Chikankata, Southern Province, Zambia
Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria
- Conditions
- First Posted Date
- 2007-06-11
- Last Posted Date
- 2008-03-26
- Lead Sponsor
- Dafra Pharma
- Target Recruit Count
- 1390
- Registration Number
- NCT00484900
- Locations
- 🇨🇲
Cameroon Baptist Convention Clinic of Biyem-Assi, Yaounde, Cameroon
🇷🇼Health centres Rwamagana and Muhima, Kigali, Rwanda
🇲🇱Health centres of Samako, Kolle and Bancoumane, Bamako, Mali
Kintampo Trial of Combination Therapy for Malaria
- Conditions
- First Posted Date
- 2005-07-13
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 510
- Registration Number
- NCT00119145
- Locations
- 🇬🇭
Kintampo Health Research Centre, Kintampo, Brong Ahafo Region, Ghana
Drug Development Updates
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