Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.
The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Ciprofloxacin is only indicated in infections caused by susceptible bacteria.
Ciprofloxacin immediate release tablets, oral suspensions, and intravenous injections are indicated for the treatment of skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections, nosocomial pneumonia, febrile neutropenia, adults who have inhaled anthrax, plague, chronic bacterial prostatitis, lower respiratory tract infections including acute exacerbations of chronic bronchitis, urinary tract infections, complicated urinary tract infections in pediatrics, complicated pyelonephritis in pediatrics, and acute sinusitis.
A ciprofloxacin otic solution and otic suspension with hydrocortisone are indicated for acute otitis externa. Ciprofloxacin suspension with dexamethasone is indicated for acute otitis media in pediatric patients with tympanostomy tubes or acute otitis externa. A ciprofloxacin intratympanic injection is indicated for pediatric patients with bilateral otitis media with effusion who are having tympanostomy tubes placed or pediatric patients 6 months or older with acute otitis externa.
A ciprofloxacin eye drop is indicated for bacterial corneal ulcers and conjunctivitis. A ciprofloxacin eye ointment is indicated for bacterial conjunctivitis.
A ciprofloxacin extended release tablet is indicated for uncomplicated urinary tract infections, complicated urinary tract infections, and acute uncomplicated pyelonephritis.
Kaiser Permanente, Los Angeles Medical Center, Los Angeles, California, United States
Sapienza University of Rome- Polo Pontino, Terracina, Latina, Italy
St. Joseph's Hospital, St. Joseph's Health Care London, London, Ontario, Canada
Houston Methodist Hospital, Houston, Texas, United States
Royal Liverpool and Broadgreen Unversity Hospitals Trust, Liverpool, Merseyside, United Kingdom
Hvidovre Hospital, Copenhagen University, Hvidovre, Copenhagen, Denmark
The Center for Pharmaceutical Research, Kansas City, Missouri, United States
Research Across America, Dallas, Texas, United States
Meridian Clinical Research, Omaha, Nebraska, United States
National University Hospital, Singapore, Singapore
Singapore General Hospital, Singapore, Singapore
Tan Tock Seng Hospital, Singapore, Singapore
Northwestern University Department of Urology, Chicago, Illinois, United States
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