Coenzyme M
- Generic Name
- Coenzyme M
- Brand Names
- Uromitexan
- Drug Type
- Small Molecule
- Chemical Formula
- C2H6O3S2
- CAS Number
- 3375-50-6
- Unique Ingredient Identifier
- VHD28S0H7F
- Background
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
- Indication
Mesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
- Associated Conditions
- Hemorrhagic cystitis caused by cyclophosphamide, Hemorrhagic cystitis caused by ifosfamide
- Associated Therapies
- -
Autologous Transplant Targeted Against Crohn's
- Conditions
- Interventions
- First Posted Date
- 2019-11-06
- Last Posted Date
- 2019-11-08
- Lead Sponsor
- Northwestern University
- Registration Number
- NCT04154735
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies
- Conditions
- Interventions
- First Posted Date
- 2019-02-21
- Last Posted Date
- 2024-08-19
- Lead Sponsor
- St. Jude Children's Research Hospital
- Target Recruit Count
- 140
- Registration Number
- NCT03849651
- Locations
- 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
Autologous Transplant To End NMO Spectrum Disorder
- First Posted Date
- 2019-02-04
- Last Posted Date
- 2019-11-20
- Lead Sponsor
- Northwestern University
- Registration Number
- NCT03829566
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States
A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC)
- Conditions
- Interventions
- First Posted Date
- 2019-01-30
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- University of Birmingham
- Target Recruit Count
- 242
- Registration Number
- NCT03821610
- Locations
- 🇬🇧
Cardiff and Vale University Health Board, Cardiff, United Kingdom
🇬🇧The Clatterbridge Cancer Centre Nhs Foundation Trust, Liverpool, United Kingdom
🇬🇧University Hospitals of Leicester Nhs Trust, Leicester, United Kingdom
Liver Transplantation With Tregs at UCSF
- Conditions
- Interventions
- First Posted Date
- 2018-08-31
- Last Posted Date
- 2024-04-23
- Target Recruit Count
- 42
- Registration Number
- NCT03654040
- Locations
- 🇺🇸
University of California, San Francisco, San Francisco, California, United States
Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2018-08-14
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- Paul Szabolcs
- Target Recruit Count
- 8
- Registration Number
- NCT03630211
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
🇺🇸Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
Cardiac Safe Transplants for Systemic Sclerosis
- First Posted Date
- 2018-07-20
- Last Posted Date
- 2020-08-12
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 9
- Registration Number
- NCT03593902
- Locations
- 🇺🇸
Northwestern University, Feinberg School of Medicine, Chicago, Illinois, United States
🇺🇸Northwestern University, Chicago, Illinois, United States
Liver Transplantation With Tregs at MGH
- Conditions
- Interventions
- First Posted Date
- 2018-07-05
- Last Posted Date
- 2023-12-08
- Target Recruit Count
- 9
- Registration Number
- NCT03577431
- Locations
- 🇺🇸
Massachusetts General Hospital: Transplantation, Boston, Massachusetts, United States
Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia
- First Posted Date
- 2018-06-29
- Last Posted Date
- 2024-10-30
- Lead Sponsor
- St. Jude Children's Research Hospital
- Target Recruit Count
- 24
- Registration Number
- NCT03573700
- Locations
- 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
Maximizing Outcome of Multiple Sclerosis Transplantation
- First Posted Date
- 2017-11-17
- Last Posted Date
- 2021-01-11
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 66
- Registration Number
- NCT03342638
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
Drug Development Updates
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