Cloxacillin

Overview

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.

Indication

Cloxacillin is indicated for the treatment of beta-hemolytic streptococcal, pneumococcal, and staphylococcal infections (including beta-lactamase producing organisms).

Associated Conditions

Infection caused by staphylococci
Infections caused by penicillinase-producing staphylococci
Pneumococcal Infection
Streptococcal Infections

Clinical Trials

Title	Posted	Study ID	Phase	Status	Sponsor
Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia	2024/12/10	NCT06726395	Phase 4	Recruiting	Region Skane
Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia	2017/08/14	NCT03248063	Not Applicable	Active, not recruiting	Assistance Publique - Hôpitaux de Paris
Efficacy of a Short-term Sequential Therapy in Non-complicated Catheter Related Bacteremia by Methicillin- Susceptible S.Aureus.	2013/06/11	NCT01875263	Phase 3	Terminated	Fundación Pública Andaluza Progreso y Salud
Staphylococcus Aureus Bacteremia Antibiotic Treatment Options	2013/02/15	NCT01792804	Phase 3	Completed	Heinrich-Heine University, Duesseldorf
Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients	2009/04/21	NCT00885300	Not Applicable	Completed	Shiraz University of Medical Sciences
Once-Daily Amikacin Plus Cloxacillin in Febrile Neutropenic Children	2005/08/12	NCT00129688	Not Applicable	Completed	Khon Kaen University
Telavancin for Treatment of Uncomplicated Staphylococcus Aureus Bacteremia	2003/06/12	NCT00062647	Phase 2	Completed	Cumberland Pharmaceuticals

FDA Drug Approvals

Approved Product	Manufacturer	NDC Code	Route	Strength	Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product	Authorization Holder	Status	Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product	Manufacturer	Approval Number	Dosage Form	Strength	Approval Date
CLOXACAP 250 CAPSULE 250 mg	HOVID BHD	SIN05036P	CAPSULE	250 mg	8/30/1990
OXACIL GRANULES 125MG/5ML	DUOPHARMA (M) SDN BHD	SIN09934P	GRANULE, FOR SUSPENSION	125 mg/5 ml	8/5/1998
CLOXACILLIN PANPHARMA FOR INJECTION 500 mg/vial	LABORATOIRES PANPHARMA	SIN07168P	INJECTION, POWDER, FOR SOLUTION	500 mg/vial	10/8/1992
MEIXAM POWDER FOR SOLUTION FOR INJECTION 500MG/VIAL	PT. MEIJI INDONESIA	SIN15834P	INJECTION, POWDER, FOR SOLUTION	500mg/vial	10/21/2019
CLOXACAP 500 CAPSULE 500 mg	HOVID BHD	SIN08889P	CAPSULE	500 mg	9/4/1996
CLOXACILLIN STRAGEN POWDER FOR SOLUTION FOR INJECTION 500 MG/VIAL	MITIM S.r.l.	SIN15001P	INJECTION, POWDER, FOR SOLUTION	500mg	5/3/2016

NMPA Drug Approvals

Approved Product	Company	Approval Number	Drug Type	Dosage Form	Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product	Registration No.	Company	Licence No.	Strength	Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product	ARTG ID	Sponsor	Registration Type	Status	Registration Date
No TGA approvals found for this drug.

Health Canada Drug Approvals

Approved Product	Company	DIN	Dosage Form	Strength	Market Date
ORBENIN INJ 250MG	ayerst laboratories	00002151	Powder For Solution - Intravenous , Intramuscular	250 MG / VIAL	12/31/1964
CLOXACILLIN SODIUM FOR INJECTION	teva canada limited	01912429	Powder For Solution - Intramuscular , Intravenous	500 MG / VIAL	12/31/1992
APO CLOXI CAP 250MG	Apotex Inc	00618292	Capsule - Oral	250 MG	12/31/1984
ORBENIN CAP 500MG	ayerst laboratories	00002054	Capsule - Oral	500 MG / CAP	12/31/1963
TEGOPEN INJ 250MG/VIAL	bristol labs division of bristol-myers squibb	00407593	Powder For Solution - Intramuscular , Intravenous	250 MG / VIAL	12/31/1973
CLOXACILLIN SODIUM FOR INJECTION	teva canada limited	01975447	Powder For Solution - Intravenous	1 G / VIAL	12/31/1992
ORBENIN INJ 2000MG	ayerst laboratories	00002186	Powder For Solution - Intravenous , Intramuscular	2 G / VIAL	12/31/1966
ORBENIN PWR 125MG/5ML	ayerst laboratories	00002445	Powder For Solution - Oral	125 MG / 5 ML	12/31/1966
APO CLOXI CAP 500MG	Apotex Inc	00618284	Capsule - Oral	500 MG	12/31/1984
ORBENIN CAP 250MG	ayerst laboratories	00002046	Capsule - Oral	250 MG / CAP	12/31/1963

CIMA AEMPS Drug Approvals

Approved Product	Company	Registration Number	Pharmaceutical Form	Prescription Type	Status
CLOXACILINA IPS 1g POLVO PARA SOLUCION INYECTABLE EFG	I P S Farma S.L.	63244	POLVO PARA SOLUCIÓN INYECTABLE	Medicamento Sujeto A Prescripción Médica	Not Commercialized

Philippines FDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product	Company	Registration Number	Dosage Form	Strength	Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name	MA Holder	MA Number	Pharmaceutical Form	Active Ingredient	Authorization Date
No UK EMC drug information found for this drug.

AI-Powered Research

Premium Access