Antithymocyte immunoglobulin (rabbit)

Generic Name
Antithymocyte immunoglobulin (rabbit)
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
308067-60-9
Unique Ingredient Identifier
D7RD81HE4W
Background

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication

For prevention of renal transplant rejection

Associated Conditions
Rejection Acute Renal
Associated Therapies
-

Randomized Trial of Induction Therapies in High Immunological Risk Kidney Transplant Recipients

First Posted Date
2008-10-31
Last Posted Date
2016-01-20
Lead Sponsor
University of Cincinnati
Target Recruit Count
40
Registration Number
NCT00782821
Locations
🇺🇸

The Christ Hospital, Cincinnati, Ohio, United States

🇺🇸

The University Hospital, Cincinnati, Ohio, United States

Prospective Pilot Study of Pre-Transplant Thymoglobulin Administration in Living Donor Renal Transplant Recipients

First Posted Date
2008-10-13
Last Posted Date
2016-01-18
Lead Sponsor
University of Cincinnati
Target Recruit Count
11
Registration Number
NCT00771745
Locations
🇺🇸

The Christ Hospital, Cincinnati, Ohio, United States

Thymoglobulin in Calcineurin Inhibitor and Steroid Minimization Protocol

Phase 4
Conditions
Interventions
First Posted Date
2008-06-27
Last Posted Date
2008-06-27
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
30
Registration Number
NCT00706680
Locations
🇨🇦

University health Network, Toronto, Ontario, Canada

🇨🇦

St Michael's Hospital, Toronto, Ontario, Canada

🇨🇦

St Paul's Hospital, Vancouver, British Columbia, Canada

Autologous Stem Cell Transplantation for Crohn's Disease

First Posted Date
2008-06-06
Last Posted Date
2024-02-14
Lead Sponsor
Paul Szabolcs
Target Recruit Count
20
Registration Number
NCT00692939
Locations
🇺🇸

UPMC Prebyterian- Adult Gastroenterology, Pittsburgh, Pennsylvania, United States

🇺🇸

Children's Hospital of Pittsburgh of UPMC-Bone Marrow Team, Pittsburgh, Pennsylvania, United States

Thymoglobulin Versus Campath-1H Versus Daclizumab in Adult, Primary Deceased Donor Renal Transplantation

First Posted Date
2008-05-28
Last Posted Date
2023-10-18
Lead Sponsor
University of Miami
Target Recruit Count
90
Registration Number
NCT00685061
Locations
🇺🇸

University of Miami Division of Transplantation, Miami, Florida, United States

Thymoglobulin Versus Campath-1H Versus Daclizumab in Adult, Primary Living Donor Renal Transplantation

First Posted Date
2008-05-21
Last Posted Date
2023-09-14
Lead Sponsor
University of Miami
Target Recruit Count
38
Registration Number
NCT00681343
Locations
🇺🇸

University of Miami Division of Transplantation, Miami, Florida, United States

Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors

First Posted Date
2008-05-19
Last Posted Date
2014-01-23
Lead Sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Target Recruit Count
30
Registration Number
NCT00679536
Locations
🇺🇸

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States

Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML

First Posted Date
2008-05-01
Last Posted Date
2015-04-22
Lead Sponsor
New York Medical College
Target Recruit Count
12
Registration Number
NCT00669890
Locations
🇺🇸

Morgan Stanley Children's Hospital of NYP, New York City, New York, United States

Autologous Transplant Followed by Allogeneic Transplant for High Risk Neuroblastoma

First Posted Date
2008-05-01
Last Posted Date
2016-06-24
Lead Sponsor
Columbia University
Target Recruit Count
15
Registration Number
NCT00670410
Locations
🇺🇸

Columbia Presbyterian Medical Center, Morgan Stanley Children's Hospital New York Presbyterian, New York, New York, United States

Prednisone Withdrawal Versus Prednisone Maintenance After Kidney Transplant

First Posted Date
2008-01-17
Last Posted Date
2017-05-15
Lead Sponsor
University of Pennsylvania
Target Recruit Count
18
Registration Number
NCT00596947
Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

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