Antithymocyte immunoglobulin (rabbit)
- Generic Name
- Antithymocyte immunoglobulin (rabbit)
- Brand Names
- -
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 308067-60-9
- Unique Ingredient Identifier
- D7RD81HE4W
- Background
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.
- Indication
For prevention of renal transplant rejection
- Associated Conditions
- Rejection Acute Renal
- Associated Therapies
- -
M-PTCy vs BuCy in Haploidentical HSCT for Acute Leukemia
- First Posted Date
- 2023-02-22
- Last Posted Date
- 2023-02-22
- Target Recruit Count
- 60
- Registration Number
- NCT05739630
- Locations
- 🇨🇳
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
A Study of TCD601 in de Novo Renal Transplant Recipients
- Conditions
- Interventions
- First Posted Date
- 2022-12-30
- Last Posted Date
- 2024-07-29
- Lead Sponsor
- ITB-Med LLC
- Target Recruit Count
- 90
- Registration Number
- NCT05669001
- Locations
- 🇺🇸
Emory University Hospital, Atlanta, Georgia, United States
🇺🇸University of Cincinnati Medical Center, Cincinnati, Ohio, United States
🇺🇸University of California San Francisco Medical Center, San Francisco, California, United States
Clinical Study of rATG Individualized Administration in Haploidentical Hematopoietic Stem Cell Transplantation
- Conditions
- Interventions
- First Posted Date
- 2022-12-02
- Last Posted Date
- 2023-02-15
- Target Recruit Count
- 90
- Registration Number
- NCT05634915
- Locations
- 🇨🇳
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
The Optimization of Haploidentical Hematopoietic Stem Cell Transplantation
- Conditions
- Interventions
- First Posted Date
- 2022-11-29
- Last Posted Date
- 2023-09-11
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT05629260
- Locations
- 🇨🇳
People's Hospital of Peking University, Beijing, Beijing, China
GVHD Prophylaxis by Addition of CD20 Monoclonal Antibody to the Conditioning Regimen in SAA With Treatment of Allo-HSCT
- First Posted Date
- 2022-08-22
- Last Posted Date
- 2022-08-24
- Target Recruit Count
- 100
- Registration Number
- NCT05510505
- Locations
- 🇨🇳
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor
- Conditions
- Interventions
- First Posted Date
- 2022-08-19
- Last Posted Date
- 2023-07-17
- Lead Sponsor
- Alice Bertaina
- Target Recruit Count
- 12
- Registration Number
- NCT05508009
- Locations
- 🇺🇸
Lucile Packard Children's Hospital, Palo Alto, California, United States
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
- Conditions
- Interventions
- Procedure: Biospecimen CollectionProcedure: Bone Marrow AspirationDrug: BusulfanDrug: CyclophosphamideProcedure: EchocardiographyDrug: FludarabineProcedure: Haploidentical Hematopoietic Cell TransplantationBiological: Lapine T-Lymphocyte Immune GlobulinProcedure: Matched Unrelated Donor Hematopoietic Cell TransplantationProcedure: Lumbar PunctureDrug: MelphalanDrug: MethotrexateProcedure: Multigated Acquisition ScanDrug: Mycophenolate MofetilProcedure: Myeloablative ConditioningOther: Quality-of-Life AssessmentOther: Questionnaire AdministrationBiological: RituximabProcedure: T-Cell Depletion TherapyRadiation: Total-Body IrradiationDrug: TacrolimusDrug: Thiotepa
- First Posted Date
- 2022-07-14
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 435
- Registration Number
- NCT05457556
- Locations
- 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸Phoenix Childrens Hospital, Phoenix, Arizona, United States
🇺🇸Arkansas Children's Hospital, Little Rock, Arkansas, United States
Pharmacologic Pretransplant Immunosuppression (PTIS) + Reduced Toxicity Conditioning (RTC) Allogeneic Stem Cell Transplantation in Inherited Hematologic Disorders
- First Posted Date
- 2022-03-24
- Last Posted Date
- 2023-09-21
- Lead Sponsor
- M.D. Anderson Cancer Center
- Registration Number
- NCT05293509
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT
- First Posted Date
- 2022-01-28
- Last Posted Date
- 2022-02-22
- Lead Sponsor
- Chinese PLA General Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT05214066
- Locations
- 🇨🇳
Chinese PLA General Hospital, Beijing, Beijing, China
GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG
- Conditions
- Interventions
- First Posted Date
- 2021-12-10
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- DKMS gemeinnützige GmbH
- Target Recruit Count
- 640
- Registration Number
- NCT05153226
- Locations
- 🇩🇪
Universitätsklinikum des Saarlandes, Homburg, Germany
🇩🇪Uniklinik RWTH Aachen, Aachen, Germany
🇩🇪Univeristätsklinikum Augsburg, Augsburg, Germany
Drug Development Updates
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