Antithymocyte immunoglobulin (rabbit)
- Generic Name
- Antithymocyte immunoglobulin (rabbit)
- Brand Names
- -
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 308067-60-9
- Unique Ingredient Identifier
- D7RD81HE4W
- Background
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.
- Indication
For prevention of renal transplant rejection
- Associated Conditions
- Rejection Acute Renal
- Associated Therapies
- -
NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic Anemia
- First Posted Date
- 2016-07-14
- Last Posted Date
- 2022-07-12
- Target Recruit Count
- 21
- Registration Number
- NCT02833805
- Locations
- 🇺🇸
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States
Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia
- Conditions
- Interventions
- First Posted Date
- 2016-07-11
- Last Posted Date
- 2024-10-17
- Lead Sponsor
- Northside Hospital, Inc.
- Target Recruit Count
- 20
- Registration Number
- NCT02828592
- Locations
- 🇺🇸
Northside Hospital, Atlanta, Georgia, United States
🇺🇸Blood and Marrow Transplant Group of Georgia, Atlanta, Georgia, United States
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
- Conditions
- Interventions
- First Posted Date
- 2016-06-06
- Last Posted Date
- 2024-10-09
- Lead Sponsor
- St. Jude Children's Research Hospital
- Target Recruit Count
- 170
- Registration Number
- NCT02790515
- Locations
- 🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States
The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Severe Aplastic Anemia
- Conditions
- Interventions
- First Posted Date
- 2016-04-20
- Last Posted Date
- 2023-03-17
- Target Recruit Count
- 60
- Registration Number
- NCT02745717
- Locations
- 🇨🇳
Shanghai general hospital, Shanghai Jiaotong university school of medicine, Shanghai, Shanghai, China
Effect of Thymoglobulin Versus Basiliximab on Regulatory T Cell Function in Live Donor Kidney Transplant Recipients
- First Posted Date
- 2016-04-06
- Last Posted Date
- 2022-09-01
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 30
- Registration Number
- NCT02730715
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Allogeneic Stem Cell Transplantation for Children With CML
- First Posted Date
- 2016-03-14
- Last Posted Date
- 2021-04-15
- Lead Sponsor
- St. Anna Kinderkrebsforschung
- Target Recruit Count
- 13
- Registration Number
- NCT02707393
- Locations
- 🇦🇹
Universitätsklinik für Kinder- und Jugendheilkunde, Graz, Austria
🇨🇿Hospital Motol, Department of Pediatric Hematology and Oncology, BMT Unit, Praha, Czechia
🇦🇹St. Anna Kinderspital, Wien, Austria
Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients
- First Posted Date
- 2016-02-17
- Last Posted Date
- 2016-02-17
- Lead Sponsor
- Associação Médico Espírita de Botucatu
- Target Recruit Count
- 48
- Registration Number
- NCT02683291
Efficacy and Safety Study of ATG for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT
- Conditions
- Interventions
- First Posted Date
- 2016-02-09
- Last Posted Date
- 2022-05-24
- Lead Sponsor
- Chinese PLA General Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT02677181
- Locations
- 🇨🇳
Liping Dou, Beijing, Beijing, China
Allo HSCT Using RIC for Hematological Diseases
- Conditions
- Interventions
- First Posted Date
- 2016-01-21
- Last Posted Date
- 2023-09-21
- Lead Sponsor
- Masonic Cancer Center, University of Minnesota
- Target Recruit Count
- 156
- Registration Number
- NCT02661035
- Locations
- 🇺🇸
Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States
Dose Study of Antithymocyteglobulin in Haploidentical Allogeneic Stem Cell Transplantation
- First Posted Date
- 2015-12-31
- Last Posted Date
- 2015-12-31
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Target Recruit Count
- 200
- Registration Number
- NCT02643589
- Locations
- 🇨🇳
Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
Drug Development Updates
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