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IDO-derived peptide vaccine/PD-L1-derived peptide vaccine (IO Biotech)

Generic Name
IDO-derived peptide vaccine/PD-L1-derived peptide vaccine (IO Biotech)

Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).

Phase 2
Recruiting
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
First Posted Date
2023-08-07
Last Posted Date
2025-02-19
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
15
Registration Number
NCT05977907
Locations
🇺🇸

Northwestern Memorial Hospital, Chicago, Illinois, United States

🇺🇸

Providence Cancer Institute, Portland, Oregon, United States

🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

and more 2 locations

Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

Phase 2
Recruiting
Conditions
Melanoma
Squamous Cell Carcinoma of Head and Neck
Interventions
First Posted Date
2022-03-15
Last Posted Date
2024-03-18
Lead Sponsor
IO Biotech
Target Recruit Count
60
Registration Number
NCT05280314
Locations
🇦🇺

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

🇺🇸

Massey Cancer Center, Richmond, Virginia, United States

🇩🇰

Aarhus University Hospital, Aarhus, Denmark

and more 12 locations

IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18)

Phase 3
Active, not recruiting
Conditions
Metastatic Melanoma
Unresectable Melanoma
Interventions
First Posted Date
2021-12-13
Last Posted Date
2024-01-09
Lead Sponsor
IO Biotech
Target Recruit Count
407
Registration Number
NCT05155254
Locations
🇳🇱

Erasmus MC, Rotterdam, Netherlands

🇦🇺

Flinders Medical Centre, Bedford Park, South Australia, Australia

🇩🇰

Herlev og Gentofte Hospital, Herlev, Denmark

and more 107 locations
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