Darifenacin
- Generic Name
- Darifenacin
- Brand Names
- Emselex, Enablex
- Drug Type
- Small Molecule
- Chemical Formula
- C28H30N2O2
- CAS Number
- 133099-04-4
- Unique Ingredient Identifier
- APG9819VLM
- Background
Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence.
Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention.
It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
- Indication
For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency and frequency.
- Associated Conditions
- Overactive Bladder Syndrome (OABS)
- Associated Therapies
- -
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