Vaborem (previosly Vabomere) is an antibiotic used in adults to treat the following infections, including when they have spread into the blood (bacteraemia): - complicated (difficult-to-treat) infections of the urinary tract, including kidneys; - complicated abdominal infections of the tissues and organs in the belly (intra-abdominal infections); - lung infections caught in hospital (hospital-acquired pneumonia), including ventilator-associated pneumonia (pneumonia caught from a ventilator, which is a machine that helps a patient to breathe). It can also be used for infections caused by Gram-negative bacteria when other treatments might not work. Vaborem contains the active substances meropenem and vaborbactam.
Therapeutic Indication
### Therapeutic indication Vaborem is indicated for the treatment of the following infections in adults: - Complicated urinary tract infection (cUTI), including pyelonephritis - Complicated intra-abdominal infection (cIAI) - Hospital-acquired pneumonia (HAP), including ventilator associated pneumonia (VAP). Treatment of patients with bacteraemia that occurs in association with, or is suspected to be associated with, any of the infections listed above. Vaborem is also indicated for the treatment of infections due to aerobic Gram-negative organisms in adults with limited treatment options. Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Therapeutic Area (MeSH)
ATC Code
J01DH
ATC Item
碳青霉烯类
Pharmacotherapeutic Group
Antibacterials for systemic use
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| meropenem trihydrate | N/A | meropenem trihydrate |
| vaborbactam | N/A | Vaborbactam |
EMA Name
Vaborem
Medicine Name
Vaborem
Aliases
N/A