<div><p paraid="1521352829" paraeid="{d9c26767-e4d3-46b8-aa7d-843168e23844}{184}">Bimervax is a vaccine for preventing coronavirus disease 2019 (COVID-19) in people aged 12 years and older. </p></div><div><p paraid="1521352831" paraeid="{d9c26767-e4d3-46b8-aa7d-843168e23844}{208}">The active substance in Bimervax is a protein produced in the laboratory that consists of part of the SARS-CoV-2 (the virus that causes COVID-19). In the originally authorised Bimervax, this protein was designed to match the protein from the Alpha and Beta variants. As SARS-CoV-2 keeps evolving, Bimervax has been adapted to target more recent strains of the virus. This helps maintain protection against COVID-19. </p></div><div><p paraid="701143927" paraeid="{8122c219-a96b-49be-9735-c37a2518a550}{19}">Three versions of Bimervax are currently authorised, with Bimervax LP.8.1 being the most recent: </p></div><div><ul role="list"><li aria-setsize="-1" data-leveltext="" data-font="Symbol" data-listid="28" data-list-defn-props='{"335551500":13209,"335552541":1,"335559685":357,"335559991":357,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}' data-aria-posinset="1" data-aria-level="1" role="listitem"><p paraid="2013570681" paraeid="{8122c219-a96b-49be-9735-c37a2518a550}{33}">Bimervax original which targets the Alpha and Beta variants of SARS-CoV-2; </p></li></ul></div><div><ul role="list"><li aria-setsize="-1" data-leveltext="" data-font="Symbol" data-listid="28" data-list-defn-props='{"335551500":13209,"335552541":1,"335559685":357,"335559991":357,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}' data-aria-posinset="2" data-aria-level="1" role="listitem"><p paraid="1438658374" paraeid="{8122c219-a96b-49be-9735-c37a2518a550}{55}">Bimervax XBB.1.16 which targets the XBB.1.16 variant of SARS-CoV-2; </p></li></ul></div><div><ul role="list"><li aria-setsize="-1" data-leveltext="" data-font="Symbol" data-listid="28" data-list-defn-props='{"335551500":13209,"335552541":1,"335559685":357,"335559991":357,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}' data-aria-posinset="3" data-aria-level="1" role="listitem"><p paraid="111199088" paraeid="{8122c219-a96b-49be-9735-c37a2518a550}{73}">Bimervax LP.8.1 which targets the LP.8.1 variant of SARS-CoV-2. </p></li></ul></div><div><p paraid="1521352833" paraeid="{8122c219-a96b-49be-9735-c37a2518a550}{79}">Bimervax does not contain the virus itself and cannot cause COVID-19. </p></div>
Therapeutic Indication
<div class="subsection mt-3-5"> <h3>Therapeutic indication</h3><p>Bimervax is indicated as a booster for active immunisation to prevent COVID-19 in individuals 12 years of age and older who have previously received a mRNA COVID-19 vaccine (see sections 4.2 and 5.1). The use of this vaccine should be in accordance with official recommendations.</p><p>Bimervax XBB.1.16 is indicated for active immunisation to prevent COVID-19 caused by SARS-CoV-2 in individuals 12 years of age and older. The use of this vaccine should be in accordance with official recommendations.</p><p>Bimervax LP.8.1 is indicated for active immunisation to prevent COVID-19 caused by SARS CoV-2 in individuals 12 years of age and older. The use of this vaccine should be in accordance with official recommendations.</p></div>
Therapeutic Area (MeSH)
ATC Code
J07BN
ATC Item
N/A
Pharmacotherapeutic Group
Vaccines
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion dimer produced by recombinant DNA technology | N/A | SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion dimer produced by recombinant DNA technology |
EMA Name
Bimervax
Medicine Name
Bimervax
Aliases
N/ANo risk management plan link.