Yuvanci is a medicine used for the long-term treatment of adults with pulmonary arterial hypertension (PAH). It contains the active substances macitentan and tadalafil and is used as a replacement for people who are already taking macitentan and tadalafil as separate medicines for PAH. People with PAH have narrowed blood vessels in the lungs, causing an abnormally high blood pressure in the arteries of the lungs and symptoms such as breathlessness and fatigue. Yuvanci is used in people with moderate or marked limitations of physical activity (corresponding to WHO functional class II or III, respectively).
Therapeutic Indication
### Therapeutic indication Yuvanci is indicated as substitution therapy for the long-term treatment of pulmonary arterial hypertension (PAH) in adult patients of WHO Functional Class (FC) II to III, who are already treated with the combination of macitentan and tadalafil given concurrently as separate tablets.
Therapeutic Area (MeSH)
ATC Code
C02KX54
ATC Item
macitentan and tadalafil
Pharmacotherapeutic Group
Antihypertensives
Active Substance (Summary)
INN / Common Names
EMA Name
Yuvanci
Medicine Name
Yuvanci
Aliases
N/ANo risk management plan link.
