Exblifep is an antibiotic used in adults to treat: - complicated (difficult to treat) infections of the urinary tract (parts of the body that collect and pass out urine), including pyelonephritis (kidney infection); - hospital-acquired pneumonia (an infection of the lungs that is caught at the hospital), including ventilator-associated pneumonia (pneumonia that develops in patients who use a machine called a ventilator to help them breathe); - bacteraemia (bacteria in the blood) when it is associated or suspected to be associated with complicated urinary tract infection or hospital-acquired pneumonia. Prescribers should consider official guidance on the appropriate use of antibiotics. Exblifep contains two active substances, cefepime and enmetazobactam.
Therapeutic Indication
### Therapeutic indication Exblifep is indicated for the treatment of the following infections in adults (see sections 4.4 and 5.1): \- Complicated urinary tract infections (cUTI), including pyelonephritis \- Hospital-acquired pneumonia (HAP), including ventilator associated pneumonia (VAP) Treatment of patients with bacteraemia that occurs in association with, or is suspected to be associated with, any of the infections listed above. Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Therapeutic Area (MeSH)
ATC Code
J01DE51
ATC Item
cefepime and beta-lactamase inhibitor
Pharmacotherapeutic Group
Antibacterials for systemic use
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| Enmetazobactam | N/A | Enmetazobactam |
| cefepime dihydrochloride monohydrate | N/A | cefepime dihydrochloride |
EMA Name
Exblifep
Medicine Name
Exblifep
Aliases
N/ANo risk management plan link.
