Pemetrexed Baxter is used to treat two types of lung cancer: - malignant pleural mesothelioma (a cancer of the lining of the lungs that is usually caused by exposure to asbestos), where it is used together with cisplatin in patients who have not received chemotherapy before and whose cancer cannot be removed by surgery; - advanced or metastatic (meaning it has spread to other parts of the body) ‘non-small-cell’ lung cancer of the kind known as ‘non-squamous’, where it is used either in combination with cisplatin in previously untreated patients or on its own in patients who have previously received cancer treatment. It can also be used as a maintenance treatment in patients who have received a platinum-based chemotherapy. Pemetrexed Baxter is a ‘generic medicine’. This means that Pemetrexed Baxter contains the same active substance and works in the same way as a ‘reference medicine’ already authorised in the EU called Alimta. For more information on generic medicines, see the question-and-answer document [here](https://www.ema.europa.eu/en/documents/medicine-qa/questions-answers-generic-medicines_en.pdf). Pemetrexed Baxter contains the active substance pemetrexed.
Therapeutic Indication
### Therapeutic indication Malignant pleural mesothelioma Pemetrexed Baxter in combination with cisplatin is indicated for the treatment of chemotherapy naïve patients with unresectable malignant pleural mesothelioma. Non-small cell lung cancer Pemetrexed Baxter in combination with cisplatin is indicated for the first line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology (see section 5.1). Pemetrexed Baxter is indicated as monotherapy for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients whose disease has not progressed immediately following platinum-based chemotherapy (see section 5.1). Pemetrexed Baxter is indicated as monotherapy for the second line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology (see section 5.1).
Therapeutic Area (MeSH)
ATC Code
L01BA04
ATC Item
pemetrexed
Pharmacotherapeutic Group
Antineoplastic agents
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| pemetrexed disodium heptahydrate | N/A | 培美曲塞二钠 |
EMA Name
Pemetrexed Baxter
Medicine Name
Pemetrexed Baxter
Aliases
N/ANo risk management plan link.