<p>Carmustine medac is a cancer medicine that is used, on its own or with other cancer medicines and treatments, to treat the following types of cancer:</p><ul><li>brain tumours, both those that develop directly in the brain and cancers that have spread from elsewhere in the body (metastatic brain tumours);</li><li>Hodgkin’s lymphoma and non-Hodgkin’s lymphomas, types of cancer that originate from white blood cells. The medicine is used when initial treatment has not worked or the cancer has come back;</li><li>tumours of stomach and bowel;</li><li>malignant melanoma (a type of skin cancer).</li></ul><p>Carmustine medac is also used as a ‘conditioning’ treatment before transplantation of the patient’s own haematopoietic progenitor cells (immature cells that are able to produce the cells of the blood) to treat Hodgkin’s lymphoma and non-Hodgkin’s lymphomas. It is used to clear the patient’s bone marrow and make room for the transplanted cells.</p><p>Carmustine medac contains the active substance carmustine and is a ‘generic medicine’. This means that Carmustine medac contains the same active substance and works in the same way as a ‘reference medicine’ already authorised in the EU called Carmubris.</p>
Therapeutic Indication
<div class="subsection mt-3-5"> <h3>Therapeutic indication</h3><p>Carmustine is indicated n adults in the following malignant neoplasms as a single agent or in combination with other antineoplastic agents and/or other therapeutic measures (radiotherapy, surgery):</p> <ul> <li>Brain tumours (glioblastoma, brain-stem gliomas, medulloblastoma, astrocytoma and ependymoma), brain metastases</li> <li>Secondary therapy in non-Hodgkin’s lymphoma and Hodgkin’s disease</li> <li>as conditioning treatment prior to autologous haematopoietic progenitor cell transplantation (HPCT) in malignant haematological diseases (Hodgkin’s disease / Non-hodgkin’s lymphoma).</li> </ul> </div>
Therapeutic Area (MeSH)
ATC Code
L01AD01
ATC Item
N/A
Pharmacotherapeutic Group
Antineoplastic agents
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| carmustine | N/A | carmustine |
EMA Name
Carmustine medac (previously Carmustine Obvius)
Medicine Name
Carmustine medac (previously Carmustine Obvius)
Aliases
N/ANo risk management plan link.