Kisplyx is a cancer medicine used to treat adults with advanced renal cell carcinoma (a type of kidney cancer). It is used with another cancer medicine, pembrolizumab, when patients have not had previous treatment for their cancer. Kisplyx is also used with the cancer medicine everolimus in patients who have been previously treated with a type of cancer medicine called a vascular endothelial growth factor (VEGF) inhibitor. Kisplyx contains the active substance lenvatinib.
Therapeutic Indication
### Therapeutic indication Kisplyx is indicated for the treatment of adults with advanced renal cell carcinoma (RCC): - in combination with pembrolizumab, as first-line treatment (see section 5.1). - in combination with everolimus, following one prior vascular endothelial growth factor (VEGF)-targeted therapy.
Therapeutic Area (MeSH)
ATC Code
L01XE29
ATC Item
xl 01 xe 29
Pharmacotherapeutic Group
Antineoplastic agents
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| lenvatinib mesilate | N/A | 仑伐替尼 |
EMA Name
Kisplyx
Medicine Name
Kisplyx
Aliases
N/A