Spherox is a medicine used to repair defects to the cartilage in the knee in patients who are experiencing symptoms (such as pain and problems moving the knee). It is used where the affected area is no larger than 10 cm². Spherox is used in adults and in adolescents whose bones in the joints have finished growing. Spherox contains spheroids (spherical aggregates) of chondrocytes, cells found in healthy cartilage, that have been prepared from the patient’s own tissues.
Therapeutic Indication
### Therapeutic indication Repair of symptomatic articular cartilage defects of the femoral condyle and the patella of the knee (International Cartilage Repair Society \[ICRS\] grade III or IV) with defect sizes up to 10 cm2 in adults.
Therapeutic Area (MeSH)
ATC Code
M09AX02
ATC Item
chondrocytes, autologous
Pharmacotherapeutic Group
Other drugs for disorders of the musculo-skeletal system
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| spheroids of human autologous matrix-associated chondrocytes | N/A | Spheroids of human autologous matrix-associated chondrocytes |
EMA Name
Spherox
Medicine Name
Spherox
Aliases
N/A