Entresto is a heart medicine used in adults with chronic (long-term) heart failure who have symptoms of the disease and reduced ejection fraction (a measure of how well the heart pumps blood). The medicine is also used in adolescents and children from 1 year of age with chronic heart failure who have symptoms of the disease and left ventricular systolic dysfunction (a problem affecting the left side of the heart). Heart failure is the inability of the heart to pump enough blood around the body. Entresto contains the active substances sacubitril and valsartan.
Therapeutic Indication
### Therapeutic indication **Paediatric heart failure** Entresto is indicated in children and adolescents aged one year or older for treatment of symptomatic chronic heart failure with left ventricular systolic dysfunction. **Adult heart failure** Entresto is indicated in adult patients for treatment of symptomatic chronic heart failure with reduced ejection fraction.
Therapeutic Area (MeSH)
ATC Code
C09DX04
ATC Item
valsartan and sacubitril
Pharmacotherapeutic Group
N/A
Active Substance (Summary)
INN / Common Names
EMA Name
Entresto
Medicine Name
Entresto
Aliases
N/ANo risk management plan link.