Pemetrexed Krka is a cancer medicine used to treat two types of lung cancer: - malignant pleural mesothelioma (a cancer of the lining of the lungs that is usually caused by exposure to asbestos), where it is used together with cisplatin in patients who have not received chemotherapy before and whose cancer cannot be removed by surgery; - advanced non-small-cell lung cancer of the kind known as ‘non-squamous’, where it is used either in combination with cisplatin in previously untreated patients or on its own in patients who have previously received cancer treatment. It can also be used as a maintenance treatment in patients who have received platinum-based chemotherapy. Pemetrexed Krka contains the active substance pemetrexed. It is a ‘generic medicine’. This means that Pemetrexed Krka contains the same active substance and works in the same way as a ‘reference medicine’ already authorised in the EU called Alimta.
Therapeutic Indication
### Therapeutic indication **Malignant pleural mesothelioma** Pemetrexed Krka in combination with cisplatin is indicated for the treatment of chemotherapy naïve patients with unresectable malignant pleural mesothelioma. **Non-small cell lung cancer** Pemetrexed Krka in combination with cisplatin is indicated for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology. Pemetrexed Krka is indicated as monotherapy for the maintenance treatment of locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients whose disease has not progressed immediately following platinum-based chemotherapy. Pemetrexed Krka is indicated as monotherapy for the second-line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology.
Therapeutic Area (MeSH)
N/AATC Code
L01BA04
ATC Item
pemetrexed
Pharmacotherapeutic Group
Antineoplastic agents
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| pemetrexed disodium | N/A | 培美曲塞二钠 |
EMA Name
Pemetrexed Krka
Medicine Name
Pemetrexed Krka
Aliases
N/ANo risk management plan link.
