Xromi is a medicine used in adults, adolescents and children over nine months of age who have sickle cell disease, a genetic disease where the red blood cells become rigid and sticky, and change from being disc-shaped to being crescent-shaped (like a sickle). Xromi is used to prevent so-called vaso-occlusive complications – problems that happen when blood vessels become blocked by the abnormal red blood cells, restricting the flow of blood to parts of the body. Xromi contains the active substance hydroxycarbamide and is a ‘hybrid medicine’. This means that it is similar to a ‘reference medicine’ containing the same active substance, but there are certain differences between the two: Xromi is given as a liquid to be swallowed rather than as capsules and is authorised for different uses. The reference medicine for Xromi is Hydrea.
Therapeutic Indication
### Therapeutic indication Xromi is indicated for the prevention of vaso-occlusive complications of Sickle Cell Disease in patients over 9 months of age.
Therapeutic Area (MeSH)
ATC Code
L01XX05
ATC Item
hydroxycarbamide
Pharmacotherapeutic Group
Antineoplastic agents
Active Substance (Summary)
INN / Common Names
| Substance | CAS | Monograph |
|---|---|---|
| hydroxycarbamide | N/A | 羟基脲 |
EMA Name
Xromi
Medicine Name
Xromi
Aliases
N/A