Beyonttra is a medicine used in adults to treat cardiomyopathy (damage to the heart muscle) caused by variant or wild\-type transthyretin amyloidosis (ATTR\-CM), a disease in which abnormal transthyretin (TTR) proteins form clumps called amyloids, which build up mainly in the heart. Variant transthyretin amyloidosis occurs when there is a mutation (change) in the gene for the TTR protein, causing it to misfold and form amyloids. In wild\-type transthyretin amyloidosis there is no gene mutation, but the TTR protein still misfolds. Beyonttra contains the active substance acoramidis.
Therapeutic Indication
For the treatment of wild\-type or variant transthyretin amyloidosis in adult patients with cardiomyopathy (ATTR\-CM).
Therapeutic Area (MeSH)
ATC Code
C01EB25
ATC Item
N/A
Pharmacotherapeutic Group
Cardiac therapy
Active Substance (Summary)
INN / Common Names
EMA Name
Beyonttra
Medicine Name
Beyonttra
Aliases
N/ANo risk management plan link.