Nucala

Nucala is used to treat: - a particular type of asthma called eosinophilic asthma in patients aged 6 years and above. It is used with other medicines in patients whose asthma is severe and not well controlled with previous treatments; - severe chronic rhinosinusitis with nasal polyps (inflamed lining of the nose and sinuses with swellings in the nose) in adults. Nucala is used with a corticosteroid given into the nose when corticosteroid given by mouth or injection with or without surgery does not work well enough; - eosinophilic granulomatosis with polyangiitis (EGPA), a disease that causes vasculitis (inflammation of blood vessels) in the lungs, heart, intestines, and nerves. This can lead to asthma, chronic sinusitis and elevated levels of a type of white blood cell called eosinophils. Nucala is used with other medicines in patients aged 6 years and above when EGPA is relapsing-remitting or not well controlled with previous treatments. ‘Relapsing-remitting’ means that the patient has flare-ups of symptoms (relapses) followed by periods of recovery (remissions); - hypereosinophilic syndrome (HES), a disease in which eosinophils start growing out of control. It is used with other medicines in adults whose disease is not well controlled with previous treatments and when the disease is linked to a blood abnormality or has no obvious cause. Nucala contains the active substance mepolizumab.