Thiotepa Riemser is used in combination with chemotherapy in two ways: * as a ‘conditioning’ (preparative) treatment before transplantation of haematopoietic progenitor cells (the cells that make blood cells). This type of transplant is used in patients who need replacement blood\-making cells because they have a blood disease such as a cancer of the blood (e.g. leukaemia) or diseases causing low red\-blood cell counts (including thalassaemia or sickle\-cell anaemia); * during the treatment of solid tumours when high\-dose chemotherapy followed by transplantation of haematopoietic progenitor cells is needed. Thiotepa Riemser can be used for transplantation of progenitor cells from a donor or for transplantation of progenitor cells from the patient’s own body. Thiotepa Riemser contains the active substance thiotepa and is a ‘generic medicine’. This means that Thiotepa Riemser contains the same active substance and works in the same way as a ‘reference medicine’ already authorised in the EU called Tepadina. For more information on generic medicines, see the question\-and\-answer document below.
Therapeutic Indication
Thiotepa Riemser is indicated, in combination with other chemotherapy medicinal products: * with or without total body irradiation (TBI), as conditioning treatment prior to allogeneic or autologous haematopoietic progenitor cell transplantation (HPCT) in haematological diseases in adult and paediatric patients; * when high dose chemotherapy with HPCT support is appropriate for the treatment of solid tumours in adult and paediatric patients. Thiotepa Riemser is indicated, in combination with other chemotherapy medicinal products: * with or without total body irradiation (TBI), as conditioning treatment prior to allogeneic or autologous haematopoietic progenitor cell transplantation (HPCT) in haematological diseases in adult and paediatric patients; * when high dose chemotherapy with HPCT support is appropriate for the treatment of solid tumours in adult and paediatric patients
Therapeutic Area (MeSH)
ATC Code
L01AC01
ATC Item
N/A
Pharmacotherapeutic Group
Antineoplastic agents
Active Substance (Summary)
INN / Common Names
EMA Name
Thiotepa Riemser
Medicine Name
Thiotepa Riemser
Aliases
N/ANo risk management plan link.