Privigen is a medicine used to treat people who: * are at risk of infection because they do not have enough antibodies, particularly immunoglobulin G (IgG). Antibodies are protein in the blood that helps the body fight infections. This includes: * people who are born with a lack of antibodies (primary immunodeficiency syndrome, PID); * people who develop a lack of antibodies after birth (secondary immunodeficiency syndrome, SID), who have low levels of IgG and suffer from infections that are severe or keep coming back despite treatment with medicines used to treat infections. * have certain immune diseases caused by the body’s own immune system attacking normal tissues. In these diseases, Privigen helps regulate the activity of the immune system (immunomodulation). These include: * primary immune thrombocytopenia (ITP), where people do not have enough platelets (components that help the blood to clot) and are at high risk of bleeding; * Guillain\-Barré syndrome or chronic inflammatory demyelinating polyneuropathy (CIDP), inflammatory disorders of the nerves that cause muscle weakness and numbness; * Kawasaki disease, a disease mainly seen in children which causes inflammation of blood vessels; * multifocal motor neuropathy, a nerve disorder that causes weakness of the arms and legs. * need protection against measles before or after exposure because they are at risk and cannot receive, or should not receive, measles vaccination. The medicine contains the active substance human normal immunoglobulin.
Therapeutic Indication
Replacement therapy in adults, and children and adolescents (0\-18 years) in: * primary immunodeficiency (PID) syndromes with impaired antibody production; * hypogammaglobulinaemia and recurrent bacterial infections in patients with chronic lymphocytic leukaemia, in whom prophylactic antibiotics have failed; * hypogammaglobulinaemia and recurrent bacterial infections in plateau\-phase\-multiple\-myeloma patients who have failed to respond to pneumococcal immunisation; * hypogammaglobulinaemia in patients after allogeneic haematopoietic\-stem\-cell transplantation (HSCT); * congenital AIDS with recurrent bacterial infections. Immunomodulation in adults, and children and adolescents (0\-18 years) in: * primary immune thrombocytopenia (ITP), in patients at high risk of bleeding or prior to surgery to correct the platelet count; * Guillain\-Barré syndrome; * Kawasaki disease; * chronic inflammatory demyelinating polyneuropathy (CIDP). Only limited experience is available of use of intravenous immunoglobulins in children with CIDP.
Therapeutic Area (MeSH)
ATC Code
J06BA02
ATC Item
N/A
Pharmacotherapeutic Group
Immune sera and immunoglobulins
Active Substance (Summary)
INN / Common Names
EMA Name
Privigen
Medicine Name
Privigen
Aliases
N/ANo risk management plan link.