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UroAv-B

UroAv-B Urinary Antiseptic (Product contract packaged by Apace Packaging, LLC)

Approved
Approval ID

6cbea1e3-1fc7-ac12-e053-2991aa0aabbe

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

May 21, 2018

Manufacturers
FDA

Apace Packaging, LLC

DUNS: 361961142

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Methenamine, Sodium Phosphate, Monobasic, Anhydrous, Phenyl Salicylate, Methylene Blue and Hyoscyamine Sulfate

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code15338-503
Product Classification
G
Generic Name
Methenamine, Sodium Phosphate, Monobasic, Anhydrous, Phenyl Salicylate, Methylene Blue and Hyoscyamine Sulfate
Product Specifications
Route of AdministrationORAL
Effective DateMay 21, 2018
FDA Product Classification

INGREDIENTS (14)

POLYETHYLENE GLYCOLSInactive
Code: 3WJQ0SDW1A
Classification: IACT
LACTOSE, UNSPECIFIED FORMInactive
Code: J2B2A4N98G
Classification: IACT
CROSPOVIDONE (15 MPA.S AT 5%)Inactive
Code: 68401960MK
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
TITANIUM DIOXIDEInactive
Code: 15FIX9V2JP
Classification: IACT
FD&C RED NO. 3Inactive
Code: PN2ZH5LOQY
Classification: IACT
GELATINInactive
Code: 2G86QN327L
Classification: IACT
METHENAMINEActive
Quantity: 118 mg in 1 1
Code: J50OIX95QV
Classification: ACTIB
PHENYL SALICYLATEActive
Quantity: 36 mg in 1 1
Code: 28A37T47QO
Classification: ACTIB
METHYLENE BLUEActive
Quantity: 10 mg in 1 1
Code: T42P99266K
Classification: ACTIB
HYOSCYAMINE SULFATEActive
Quantity: 0.12 mg in 1 1
Code: F2R8V82B84
Classification: ACTIB
SODIUM PHOSPHATE, MONOBASIC, ANHYDROUSActive
Quantity: 40.8 mg in 1 1
Code: KH7I04HPUU
Classification: ACTIB

Drug Labeling Information

INDICATIONS & USAGE SECTION

LOINC: 34067-9Updated: 3/25/2016

INDICATIONS AND USAGE

UroAv-B Capsules are indicated for the treatment of symptoms of irritative voiding.

Indicated for the relief of local symptoms, such as inflammation, hypermotility, and pain, which accompany lower urinary tract infections.

Indicated for the relief of urinary tract symptoms caused by diagnostic procedures.

HOW SUPPLIED SECTION

LOINC: 34069-5Updated: 3/25/2016

HOW SUPPLIED

UroAv-B Capsules are blue capsules imprinted with 200, available in bottles of 100 capsules, (NDC: 42291-852-01).

SPL UNCLASSIFIED SECTION

LOINC: 42229-5Updated: 7/16/2015

Rx Only

DESCRIPTION SECTION

LOINC: 34089-3Updated: 3/25/2016

DESCRIPTION

UroAv-B Capsules for oral administration.

Each tablet contains:
Methenamine 118 mg
Sodium Phosphate Monobasic 40.8 mg
Phenyl Salicylate 36 mg
Methylene Blue 10 mg
Hyoscyamine Sulfate 0.12 mg

Inactive ingredients: Lactose, Polyethylene Glycol, Crospovidone, Magnesium Stearate, Colloidal Silicon Dioxide, FD&C Blue # 1, FD&C Red # 3, Titanium Dioxide, Gelatin.

METHENAMINE. [100-97-0] 1,3,5,7-Tetraazatricyclo [3.3.1.-1 3,7] decane; hexamethylenetetramine; HMT; HMTA; hexamine; 1,3,5,7-tetraazaadamantane hexamethylenemine; Uritone; Urotropin. C 6H 12N 4; mol wt 140.19; C 51.40%, H 8.63%, N 39.96%. Methenamine (hexamethylenetetramine) exists as colorless, lustrous crystals or white crystalline powder. Its solutions are alkaline to litmus. Freely soluble in water, soluble in alcohol and in chloroform.

SODIUM PHOSPHATE MONOBASIC. [7558-80-7] Phosphoric acid sodium salt (1:1); Sodium biphosphate; sodium dihydrogen phosphate; acid sodium phosphate; monosodium orthophosphate; primary sodium phosphate; H 2NaO 4P; mol wt 119.98, H 1.68%, Na 19.16%, O 53.34%, P 25.82%. Monohydrate, white, odorless slightly deliquesce crystals or granules. At 100° C loses all its water; when ignited it converts to metaphosphate. It is freely soluble in water and practically insoluble in alcohol. The aqueous solution is acid. pH of 0.1 molar aqueous solution at 25° C: 4.5.

PHENYL SALICYLATE. [118-55-8] 2-Hydroxybenzoic acid phenyl ester; Salol. C 13H 10O 3; mol wt 214.22, C 72.89%, H 4.71%, O 22.41%. Made by the action of phosphorus oxy-chloride on a mixture of phenol and salicylic acid. Phenyl Salicylate exists as white crystals with a melting point of 41°-43° C. It is very slightly soluble in water and freely soluble in alcohol.

METHYLENE BLUE. [61-73-4] 3,7-Bis(dimethylamino) phenothiazin-5-ium chloride; C.I. Basic Blue 9; methylthioninium chloride; tetramethylthionine chloride; 3,7-bis(dimethylamino) phenazathionium chloride. C 16H 18ClN 3S; mol wt 319.85, C 60.08%, H 5.67%, Cl 11.08%, N 13.14%, S 10.03%. Methylene Blue (Methylthionine chloride) exists as dark green crystals. It is soluble in water and in chloroform; sparingly soluble in alcohol.

HYOSCYAMINE SULFATE. [620-61-1] [3(S)-endo]-α-(Hydroxymethyl)-benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate(2:1)(salt); 1αH,5αH- tropan-3α-ol(-)-tropate (ester) sulfate(2:1)(salt); 3α-tropanyl S-(-)-tropate; I-tropic acid ester with tropine; I-tropine tropate. C 34H 48N 2O 10S. Hyoscyamine Sulfate is an alkaloid of belladonna. Exists as a white crystalline powder. Its solutions are alkaline to litmus. Affected by light, it is slightly soluble in water; freely soluble in alcohol; sparingly soluble in ether.

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UroAv-B - FDA Drug Approval Details