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Meclizine Hydrochloride

These highlights do not include all the information needed to use MECLIZINE HYDROCHLORIDE safely and effectively. See full prescribing information for MECLIZINE HYDROCHLORIDE. MECLIZINE hydrochloride tablets, for oral use MECLIZINE hydrochloride chewable tablets, for oral use Initial U.S. Approval: 1957

Approved
Approval ID

112103bc-25e2-42cf-8542-ba1d3392a2c3

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Aug 20, 2025

Manufacturers
FDA

Bryant Ranch Prepack

DUNS: 171714327

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Meclizine Hydrochloride

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code71335-1872
Application NumberNDA010721
Product Classification
M
Marketing Category
C73605
G
Generic Name
Meclizine Hydrochloride
Product Specifications
Route of AdministrationORAL
Effective DateAugust 20, 2025
FDA Product Classification

INGREDIENTS (9)

STARCH, CORNInactive
Code: O8232NY3SJ
Classification: IACT
WATERInactive
Code: 059QF0KO0R
Classification: IACT
SUCROSEInactive
Code: C151H8M554
Classification: IACT
POLYETHYLENE GLYCOL, UNSPECIFIEDInactive
Code: 3WJQ0SDW1A
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
ALCOHOLInactive
Code: 3K9958V90M
Classification: IACT
MECLIZINE HYDROCHLORIDEActive
Quantity: 12.5 mg in 1 1
Code: HDP7W44CIO
Classification: ACTIB
ANHYDROUS DIBASIC CALCIUM PHOSPHATEInactive
Code: L11K75P92J
Classification: IACT

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 12/30/2011

Meclizine Hcl 12.5mg Tablet

Label

DESCRIPTION SECTION

LOINC: 34089-3Updated: 8/29/2019

11 DESCRIPTION

Meclizine hydrochloride, a histamine (H1) receptor antagonist, is a white or slightly yellowish, crystalline powder. It has the following structural formula:

struct-1

Chemically, meclizine hydrochloride is 1-(p-chloro-α- phenylbenzyl)-4-(m-methylbenzyl) piperazine dihydrochloride monohydrate.

Tablets
Inactive ingredients for the tablets are: corn starch; dibasic calcium phosphate; magnesium stearate; polyethylene glycol; sucrose. The 12.5 mg tablets also contain: FD&C Blue # 1. The 25 mg tablets also contain: FD&C Yellow # 6 and D&C Yellow # 10. The 50 mg tablets also contain: FD&C Blue # 1, FD&C Yellow # 6 and D&C Yellow # 10.

Each meclizine hydrochloride 12.5 mg tablet contains 12.5 mg of meclizine dihydrochloride equivalent to 10.53 mg of meclizine free base.
Each meclizine hydrochloride 25 mg tablet contains 25 mg of meclizine dihydrochloride equivalent to 21.07 mg of meclizine free base.
Each meclizine hydrochloride 50 mg tablet contains 50 mg of meclizine dihydrochloride equivalent to 42.14 mg of meclizine free base.

Chewable Tablets
Inactive ingredients for the chewable tablets are: corn starch, colloidal silicon dioxide, FD&C Red # 40, lactose monohydrate, magnesium stearate, raspberry flavor, saccharin sodium, and talc.

Each meclizine hydrochloride 25 mg chewable tablet contains 25 mg of meclizine dihydrochloride equivalent to 21.07 mg of meclizine free base.

HOW SUPPLIED SECTION

LOINC: 34069-5Updated: 8/20/2025

16 HOW SUPPLIED/STORAGE AND HANDLING

Meclizine hydrochloride 12.5 mg tablets are oval shaped, biconvex, two-layered tablet, one blue to pale blue layer debossed with “34” and one white to off white layer debossed with “L”.

NDC: 71335-1872-1: 30 Tablets in a BOTTLE

NDC: 71335-1872-2: 60 Tablets in a BOTTLE

NDC: 71335-1872-3: 90 Tablets in a BOTTLE

NDC: 71335-1872-4: 28 Tablets in a BOTTLE

NDC: 71335-1872-5: 20 Tablets in a BOTTLE

NDC: 71335-1872-6: 120 Tablets in a BOTTLE

NDC: 71335-1872-7: 100 Tablets in a BOTTLE

NDC: 71335-1872-8: 10 Tablets in a BOTTLE

Store at 20oC to 25oC (68oF to 77oF) [See USP Controlled Room Temperature].
Dispense in a tight, light-resistant container (USP).

Repackaged/Relabeled by:
Bryant Ranch Prepack, Inc.
Burbank, CA 91504

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Meclizine Hydrochloride - FDA Drug Approval Details