MedPath

Flucytosine

FLUCYTOSINE Capsules USPRx only

Approved
Approval ID

5721b46a-4a9f-46c2-8804-a9bad4d5f80a

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Aug 26, 2025

Manufacturers
FDA

Lupin Pharmaceuticals,Inc.

DUNS: 089153071

Products 2

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Flucytosine

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code43386-771
Application NumberANDA204652
Product Classification
M
Marketing Category
C73584
G
Generic Name
Flucytosine
Product Specifications
Route of AdministrationORAL
Effective DateAugust 26, 2025
FDA Product Classification

INGREDIENTS (17)

LACTOSE MONOHYDRATEInactive
Code: EWQ57Q8I5X
Classification: IACT
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
FLUCYTOSINEActive
Quantity: 250 mg in 1 1
Code: D83282DT06
Classification: ACTIB
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
TALCInactive
Code: 7SEV7J4R1U
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
TITANIUM DIOXIDEInactive
Code: 15FIX9V2JP
Classification: IACT
FERROSOFERRIC OXIDEInactive
Code: XM0M87F357
Classification: IACT
GELATINInactive
Code: 2G86QN327L
Classification: IACT
SODIUM STARCH GLYCOLATE TYPE A POTATOInactive
Code: 5856J3G2A2
Classification: IACT
WATERInactive
Code: 059QF0KO0R
Classification: IACT
SODIUM LAURYL SULFATEInactive
Code: 368GB5141J
Classification: IACT
SODIUM HYDROXIDEInactive
Code: 55X04QC32I
Classification: IACT
SHELLACInactive
Code: 46N107B71O
Classification: IACT
POTASSIUM HYDROXIDEInactive
Code: WZH3C48M4T
Classification: IACT
POVIDONEInactive
Code: FZ989GH94E
Classification: IACT
FD&C RED NO. 40Inactive
Code: WZB9127XOA
Classification: IACT

Flucytosine

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code43386-770
Application NumberANDA204652
Product Classification
M
Marketing Category
C73584
G
Generic Name
Flucytosine
Product Specifications
Route of AdministrationORAL
Effective DateAugust 26, 2025
FDA Product Classification

INGREDIENTS (15)

MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
FLUCYTOSINEActive
Quantity: 500 mg in 1 1
Code: D83282DT06
Classification: ACTIB
LACTOSE MONOHYDRATEInactive
Code: EWQ57Q8I5X
Classification: IACT
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
TALCInactive
Code: 7SEV7J4R1U
Classification: IACT
GELATINInactive
Code: 2G86QN327L
Classification: IACT
SHELLACInactive
Code: 46N107B71O
Classification: IACT
POTASSIUM HYDROXIDEInactive
Code: WZH3C48M4T
Classification: IACT
WATERInactive
Code: 059QF0KO0R
Classification: IACT
POVIDONEInactive
Code: FZ989GH94E
Classification: IACT
TITANIUM DIOXIDEInactive
Code: 15FIX9V2JP
Classification: IACT
FERROSOFERRIC OXIDEInactive
Code: XM0M87F357
Classification: IACT
SODIUM STARCH GLYCOLATE TYPE A POTATOInactive
Code: 5856J3G2A2
Classification: IACT
SODIUM HYDROXIDEInactive
Code: 55X04QC32I
Classification: IACT
FD&C RED NO. 40Inactive
Code: WZB9127XOA
Classification: IACT

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 8/26/2025

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Flucytosine Capsules USP, 250 mg

30 Capsules

250-30

Flucytosine Capsules USP, 500 mg

100 Capsules

500-100

DESCRIPTION SECTION

LOINC: 34089-3Updated: 8/26/2025

DESCRIPTION

Flucytosine Capsules USP, an antifungal agent, is available as 250 mg and 500 mg capsules for oral administration. In addition to the active ingredient of flucytosine, each capsule contains lactose monohydrate, colloidal silicon dioxide, talc, sodium starch glycolate, magnesium stearate and hard gelatin capsule shell which contains gelatin, purified water, black iron oxide, FD&C Blue No.1, titanium dioxide and sodium lauryl sulfate for 250 mg strength; gelatin, purified water, black iron oxide and titanium dioxide for 500 mg strength. The imprinting ink contains black iron oxide, shellac, potassium hydroxide, titanium dioxide, povidone, sodium hydroxide and FD &C Red No. 40 aluminum lake for 250 mg and 500 mg strengths. Chemically, flucytosine is 5-fluorocytosine, a fluorinated pyrimidine which is related to fluorouracil and floxuridine. It is a white or almost white, crystalline powder with a molecular weight of 129.09 and the following structural formula:

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HOW SUPPLIED SECTION

LOINC: 34069-5Updated: 8/26/2025

HOW SUPPLIED

Flucytosine Capsules USP, 250 mg are size 2 hard gelatin capsule with blue opaque cap and grey opaque body imprinted with "NL771" on the cap with black ink and "250" on the body with red ink filled with white to off white powder.

Bottles of 30 (NDC 43386-771-03)

Bottles of 100 (NDC 43386-771-01).

Flucytosine Capsules USP, 500 mg are size 0 hard gelatin capsule with grey opaque cap and white opaque body imprinted "NL770" on the cap with black ink and "500" on the body with red ink, filled with white to off white powder.

Bottles of 30 (NDC 43386-770-03)

Bottles of 100 (NDC 43386-770-01).

Store at 25°C (77°F); excursions permitted to 15°C - 30°C (59°F - 86°F).

LUPIN and the Image are registered trademarks of Lupin Pharmaceuticals, Inc.

Manufactured by:

Novel Laboratories, Inc.

Somerset, NJ 08873

Manufactured for:

Lupin Pharmaceuticals, Inc.

Naples, FL 34108

SAP code: 276392

Rev: 10/2024

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Flucytosine - FDA Drug Approval Details