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Nitrofurantoin Monohydrate/ Macrocrystalline

Nitrofurantoin Capsules, USP (monohydrate/macrocrystals)

Approved
Approval ID

a4afd48b-003f-4ffa-9ca0-9432b8b0e22b

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Jan 4, 2024

Manufacturers
FDA

REMEDYREPACK INC.

DUNS: 829572556

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Nitrofurantoin Monohydrate/Macrocrystalline

PRODUCT DETAILS

NDC Product Code70518-0265
Application NumberNDA020064
Marketing CategoryC73594
Route of AdministrationORAL
Effective DateJanuary 4, 2024
Generic NameNitrofurantoin Monohydrate/Macrocrystalline

INGREDIENTS (14)

CARBOMER HOMOPOLYMER TYPE B (ALLYL SUCROSE CROSSLINKED)Inactive
Code: Z135WT9208
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
D&C YELLOW NO. 10Inactive
Code: 35SW5USQ3G
Classification: IACT
STARCH, CORNInactive
Code: O8232NY3SJ
Classification: IACT
FD&C RED NO. 40Inactive
Code: WZB9127XOA
Classification: IACT
GELATIN, UNSPECIFIEDInactive
Code: 2G86QN327L
Classification: IACT
LACTOSE, UNSPECIFIED FORMInactive
Code: J2B2A4N98G
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
POVIDONE, UNSPECIFIEDInactive
Code: FZ989GH94E
Classification: IACT
TALCInactive
Code: 7SEV7J4R1U
Classification: IACT
TITANIUM DIOXIDEInactive
Code: 15FIX9V2JP
Classification: IACT
SUCROSEInactive
Code: C151H8M554
Classification: IACT
NITROFURANTOINActive
Quantity: 25 mg in 1 1
Code: 927AH8112L
Classification: ACTIB
NITROFURANTOIN MONOHYDRATEActive
Quantity: 75 mg in 1 1
Code: E1QI2CQQ1I
Classification: ACTIM

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 11/10/2023

DRUG: Nitrofurantoin Monohydrate/ Macrocrystalline

GENERIC: Nitrofurantoin Monohydrate/Macrocrystalline

DOSAGE: CAPSULE

ADMINSTRATION: ORAL

NDC: 70518-0265-0

NDC: 70518-0265-1

NDC: 70518-0265-2

NDC: 70518-0265-3

COLOR: yellow

SHAPE: CAPSULE

SCORE: No score

SIZE: 20 mm

IMPRINT: Macrobid;52427285

PACKAGING: 30 in 1 BLISTER PACK

PACKAGING: 14 in 1 BOTTLE PLASTIC

PACKAGING: 14 in 1 BLISTER PACK

PACKAGING: 10 in 1 BOTTLE PLASTIC

ACTIVE INGREDIENT(S):

  • NITROFURANTOIN MONOHYDRATE 75mg in 1
  • NITROFURANTOIN 25mg in 1

INACTIVE INGREDIENT(S):

  • CARBOMER HOMOPOLYMER TYPE B (ALLYL SUCROSE CROSSLINKED)
  • STARCH, CORN
  • D&C YELLOW NO. 10
  • FD&C BLUE NO. 1
  • FD&C RED NO. 40
  • GELATIN, UNSPECIFIED
  • LACTOSE, UNSPECIFIED FORM
  • MAGNESIUM STEARATE
  • POVIDONE, UNSPECIFIED
  • TALC
  • TITANIUM DIOXIDE
  • SUCROSE

MM4

DESCRIPTION SECTION

LOINC: 34089-3Updated: 11/10/2023

DESCRIPTION

Nitrofurantoin is an antibacterial agent specific for urinary tract infections. Nitrofurantoin capsules, USP (monohydrate/macrocrystals) is a hard gelatin capsule. Each capsule contains 100 mg of nitrofurantoin in the form of 25 mg of nitrofurantoin macrocrystals and 75 mg of nitrofurantoin monohydrate.

The chemical name of nitrofurantoin macrocrystals is 1-[[[5-nitro-2-furanyl]methylene]amino]-2,4-imidazolidinedione. The chemical structure is the following:

structure-1

Molecular Weight: 238.16

The chemical name of nitrofurantoin monohydrate is 1-[[[5-nitro-2-furanyl]methylene]amino]-2,4- imidazolidinedione monohydrate. The chemical structure is the following:

structure-2

Molecular Weight: 256.17

**Inactive Ingredients:**Each capsule contains carbomer 934P, corn starch, compressible sugar, D&C Yellow No. 10, edible gray ink, FD&C Blue No. 1, FD&C Red No. 40, gelatin, lactose, magnesium stearate, povidone, talc, and titanium dioxide.

Meets USP Dissolution Test 8.

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Nitrofurantoin Monohydrate/ Macrocrystalline - FDA Approval | MedPath