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FDA Approval

Nilutamide

FDA-approved pharmaceutical product with comprehensive regulatory information, manufacturing details, and complete labeling documentation.

FDA Approval Summary

Company
Prasco Laboratories
DUNS: 065969375
Effective Date
December 10, 2021
Labeling Type
Human Prescription Drug Label
Nilutamide(150 mg in 1 1)

Products1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Nilutamide

Product Details

NDC Product Code
66993-212
Application Number
NDA020169
Marketing Category
NDA authorized generic (C73605)
Route of Administration
ORAL
Effective Date
November 22, 2019
STARCH, CORNInactive
Code: O8232NY3SJClass: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30Class: IACT
LACTOSEInactive
Code: J2B2A4N98GClass: IACT
DOCUSATE SODIUMInactive
Code: F05Q2T2JA0Class: IACT
TALCInactive
Code: 7SEV7J4R1UClass: IACT
Code: 51G6I8B902Class: ACTIBQuantity: 150 mg in 1 1
POVIDONEInactive
Code: FZ989GH94EClass: IACT

Drug Labeling Information

Complete FDA-approved labeling information including indications, dosage, warnings, contraindications, and other essential prescribing details.

DESCRIPTION SECTION

DESCRIPTION

Nilutamide tablets contain nilutamide, a nonsteroidal, orally active antiandrogen having the chemical name 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione with the following structural formula:

nilutamide-01.jpg

Nilutamide is a microcrystalline, white to practically white powder with a molecular weight of 317.25. Its molecular formula is C12H10F3N3O4.

It is freely soluble in ethyl acetate, acetone, chloroform, ethyl alcohol, dichloromethane, and methanol. It is slightly soluble in water [<0.1% W/V at 25°C (77°F)]. It melts between 153°C and 156°C (307.4°F and 312.8°F).

Each Nilutamide tablet contains 150 mg of nilutamide. Other ingredients in Nilutamide tablets are corn starch, lactose, povidone, docusate sodium, magnesium stearate, and talc.


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