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Azathioprine Sodium

AZATHIOPRINE SODIUM FOR INJECTION, USP

Approved
Approval ID

9ffe79a1-ac91-4a7b-a9e3-7c84bfa9ddf0

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

May 15, 2023

Manufacturers
FDA

Hikma Pharmaceuticals USA Inc.

DUNS: 001230762

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Azathioprine Sodium

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code0143-9566
Application NumberANDA074419
Product Classification
M
Marketing Category
C73584
G
Generic Name
Azathioprine Sodium
Product Specifications
Route of AdministrationINTRAVENOUS
Effective DateMay 15, 2023
FDA Product Classification

INGREDIENTS (3)

AZATHIOPRINE SODIUMActive
Quantity: 100 mg in 10 mL
Code: AM94R510MS
Classification: ACTIM
HYDROCHLORIC ACIDInactive
Code: QTT17582CB
Classification: IACT
SODIUM HYDROXIDEInactive
Code: 55X04QC32I
Classification: IACT

Drug Labeling Information

INDICATIONS & USAGE SECTION

LOINC: 34067-9Updated: 5/15/2023

INDICATIONS AND USAGE

Azathioprine Sodium for Injection, USP is indicated as an adjunct for the prevention of rejection in renal homotransplantation. It is also indicated for the management of active rheumatoid arthritis to reduce signs and symptoms.

Renal Homotransplantation

Azathioprine is indicated as an adjunct for the prevention of rejection in renal homotransplantation. Experience with over 16,000 transplants shows a five-year patient survival of 35% to 55%, but this is dependent on donor, match for HLA antigens, anti-donor or anti-B-cell alloantigen antibody and other variables. The effect of azathioprine on these variables has not been tested in controlled trials.

Rheumatoid Arthritis

Azathioprine is indicated for the treatment of active rheumatoid arthritis (RA) to reduce signs and symptoms. Aspirin, non-steroidal anti-inflammatory drugs and/or low dose glucocorticoids may be continued during treatment with azathioprine. The combined use of azathioprine with disease modifying anti- rheumatic drugs (DMARDs) has not been studied for either added benefit or unexpected adverse effects. The use of azathioprine with these agents cannot be recommended.

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Azathioprine Sodium - FDA Drug Approval Details