MedPath

Oxymetazoline hydrochloride

Oxymetazoline Hydrochloride 0.05% Nasal Spray

Approved
Approval ID

3dce34f0-9f6d-8151-e063-6394a90a1d38

Product Type

HUMAN OTC DRUG LABEL

Effective Date

Sep 2, 2025

Manufacturers
FDA

Prodose, Inc.

DUNS: 119371190

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Oxymetazoline hydrochloride

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code68210-5056
Application NumberM012
Product Classification
M
Marketing Category
C200263
G
Generic Name
Oxymetazoline hydrochloride
Product Specifications
Route of AdministrationNASAL
Effective DateSeptember 2, 2025
FDA Product Classification

INGREDIENTS (11)

BENZALKONIUM CHLORIDEInactive
Code: F5UM2KM3W7
Classification: IACT
EDETATE DISODIUMInactive
Code: 7FLD91C86K
Classification: IACT
CARBOXYMETHYLCELLULOSE SODIUMInactive
Code: K679OBS311
Classification: IACT
WATERInactive
Code: 059QF0KO0R
Classification: IACT
CELLULOSE, MICROCRYSTALLINEInactive
Code: OP1R32D61U
Classification: IACT
SODIUM PHOSPHATE, DIBASICInactive
Code: GR686LBA74
Classification: IACT
SODIUM PHOSPHATE, MONOBASICInactive
Code: 3980JIH2SW
Classification: IACT
BENZYL ALCOHOLInactive
Code: LKG8494WBH
Classification: IACT
OXYMETAZOLINE HYDROCHLORIDEActive
Quantity: 0.05 g in 100 mL
Code: K89MJ0S5VY
Classification: ACTIB
POLYETHYLENE GLYCOL, UNSPECIFIEDInactive
Code: 3WJQ0SDW1A
Classification: IACT
POVIDONEInactive
Code: FZ989GH94E
Classification: IACT

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 9/3/2025

PRINCIPAL DISPLAY PANEL - 15 mL Bottle Carton

Carton label

INDICATIONS & USAGE SECTION

LOINC: 34067-9Updated: 9/3/2025

Uses

  • temporarily relieves nasal congestion due to:

  • common cold

  • hay fever

  • upper respiratory allergies

  • temporarily relieves sinus congestion and pressure

shrinks swollen nasal membranes so you can breathe more freely

OTC - ACTIVE INGREDIENT SECTION

LOINC: 55106-9Updated: 9/3/2025

Active ingredient

Oxymetazoline hydrochloride 0.05%

OTC - PURPOSE SECTION

LOINC: 55105-1Updated: 9/3/2025

Purpose

Nasal decongestant

WARNINGS SECTION

LOINC: 34071-1Updated: 9/3/2025

Warnings

OTC - ASK DOCTOR SECTION

LOINC: 50569-3Updated: 9/3/2025

Ask a doctor before use if you have

  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland

OTC - WHEN USING SECTION

LOINC: 50567-7Updated: 9/3/2025

When using this product

  • do not use more than directed
  • do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen.
  • temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur
  • use of this container by more than one person may spread infection

OTC - STOP USE SECTION

LOINC: 50566-9Updated: 9/3/2025

Stop use and ask a doctor if symptoms persist

OTC - PREGNANCY OR BREAST FEEDING SECTION

LOINC: 53414-9Updated: 9/3/2025

If pregnant or breast-feeding, ask a health professional before use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

LOINC: 50565-1Updated: 9/3/2025

**Keep out of reach of children.**If swallowed, get medical help or contact a Poison Control Center right away.

DOSAGE & ADMINISTRATION SECTION

LOINC: 34068-7Updated: 9/3/2025

Directions

  • adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period.
  • children under 6 years of age: ask a doctor.

Shake well before use. Before using the first time, remove the protective cap from the tip and prime metered pump by depressing pump firmly several times. To spray, hold bottle with thumb at base and nozzle between first and second fingers. Without tilting head, insert nozzle into nostril. Fully depress rim with a firm, even stroke and sniff deeply. Wipe nozzle clean after use.

OTHER SAFETY INFORMATION

LOINC: 60561-8Updated: 9/3/2025

Other information

  • store between 20° to 25°C (68° to 77°F)
  • retain carton for future reference on full labelling

INACTIVE INGREDIENT SECTION

LOINC: 51727-6Updated: 9/3/2025

Inactive ingredients

benzalkonium chloride solution, benzyl alcohol, edetate disodium, flavor, microcrystalline cellulose and carboxymethylcellulose sodium, polyethylene glycol, povidone, purified water, sodium phosphate dibasic, sodium phosphate monobasic

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.