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Orphenadrine Citrate, Aspirin and Caffeine

Orphenadrine Citrate, Aspirin and Caffeine tablets 50 mg/ 770 mg/ 60 mg USP

Approved
Approval ID

7776aae6-3cbd-4aed-9aac-4bed80339e27

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Jun 19, 2023

Manufacturers
FDA

Atland Pharmaceuticals, LLC

DUNS: 080942150

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Orphenadrine Citrate, Aspirin and Caffeine

PRODUCT DETAILS

NDC Product Code71993-307
Application NumberANDA075141
Marketing CategoryC73584
Route of AdministrationORAL
Effective DateJune 19, 2023
Generic NameOrphenadrine Citrate, Aspirin and Caffeine

INGREDIENTS (12)

ZINC STEARATEInactive
Code: H92E6QA4FV
Classification: IACT
POVIDONEInactive
Code: FZ989GH94E
Classification: IACT
ORPHENADRINE CITRATEActive
Quantity: 50 mg in 1 1
Code: X0A40N8I4S
Classification: ACTIB
CAFFEINEActive
Quantity: 60 mg in 1 1
Code: 3G6A5W338E
Classification: ACTIB
ANHYDROUS LACTOSEInactive
Code: 3SY5LH9PMK
Classification: IACT
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
D&C YELLOW NO. 10Inactive
Code: 35SW5USQ3G
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
STARCH, CORNInactive
Code: O8232NY3SJ
Classification: IACT
STEARIC ACIDInactive
Code: 4ELV7Z65AP
Classification: IACT
WATERInactive
Code: 059QF0KO0R
Classification: IACT
ASPIRINActive
Quantity: 770 mg in 1 1
Code: R16CO5Y76E
Classification: ACTIB

Drug Labeling Information

PRECAUTIONS SECTION

LOINC: 42232-9Updated: 1/9/2023

PRECAUTIONS

Confusion, anxiety and tremors have been reported in a few patients receiving propoxyphene and orphenadrine concomitantly. As these symptoms may be simply due to an additive effect, reduction of dosage and/or discontinuation of one or both agents is recommended in such cases.

Safety of continuous long term therapy with Orphenadrine Citrate, Aspirin and Caffeine Tablets has not been established; therefore, if Orphenadrine Citrate, Aspirin and Caffeine Tablets are prescribed for prolonged use, periodic monitoring of blood, urine and liver function values is recommended.

Pregnancy

Embryo-Fetal Toxicity

Inform pregnant women to avoid use of aspirin and other NSAIDs starting at 30 weeks gestation because of the risk of the premature closing of the fetal ductus arteriosus. If treatment with Orphenadrine Citrate, Aspirin and Caffeine Tablets is needed for a pregnant woman between about 20 to 30 weeks gestation, advise her that she may need to be monitored for oligohydramnios, if treatment continues for longer than 48 hours [ see WARNINGS; Fetal Toxicity, PRECAUTIONS; Pregnancy] .

Serious Skin Reactions, including DRESS

Advise patients to stop taking Orphenadrine Citrate, Aspirin and Caffeine Tablets immediately if they develop any type of rash or fever and to contact their healthcare provider as soon as possible [ see Warnings].

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Orphenadrine Citrate, Aspirin and Caffeine - FDA Drug Approval Details