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FDA Approval

SIMBRINZA

FDA-approved pharmaceutical product with comprehensive regulatory information, manufacturing details, and complete labeling documentation.

FDA Approval Summary

Company
Effective Date
May 16, 2023
Labeling Type
HUMAN PRESCRIPTION DRUG LABEL
Brinzolamide(10 mg in 1 mL)
Brimonidine(2 mg in 1 mL)

Registrants1

Companies and organizations registered with the FDA for this drug approval, including their contact information and regulatory details.

Alcon Research, LLC

007672236

Manufacturing Establishments2

FDA-registered manufacturing facilities and establishments involved in the production, packaging, or distribution of this drug product.

Alcon Research, LLC

Alcon Laboratories, Inc.

Alcon Research, LLC

007672236

S.A. Alcon-Couvreur N.V.

Alcon Laboratories, Inc.

Alcon Research, LLC

370205429

Products1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

SIMBRINZA

Product Details

NDC Product Code
0065-4147
Application Number
NDA204251
Marketing Category
NDA (C73594)
Route of Administration
OPHTHALMIC
Effective Date
May 16, 2023
Code: 9451Z89515Class: ACTIBQuantity: 10 mg in 1 mL
Code: 4S9CL2DY2HClass: ACTIBQuantity: 2 mg in 1 mL
MannitolInactive
Code: 3OWL53L36AClass: IACT
Benzalkonium ChlorideInactive
Code: F5UM2KM3W7Class: IACT
Carbomer Homopolymer Type B (allyl Pentaerythritol Crosslinked)Inactive
Code: HHT01ZNK31Class: IACT
Boric AcidInactive
Code: R57ZHV85D4Class: IACT
Propylene GlycolInactive
Code: 6DC9Q167V3Class: IACT
Sodium ChlorideInactive
Code: 451W47IQ8XClass: IACT
TyloxapolInactive
Code: Y27PUL9H56Class: IACT
WaterInactive
Code: 059QF0KO0RClass: IACT
Hydrochloric AcidInactive
Code: QTT17582CBClass: IACT
Sodium HydroxideInactive
Code: 55X04QC32IClass: IACT
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