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Nitrofurantoin

Nitrofurantoin Capsules, USP (Monohydrate/Macrocrystals), 100 mg (Twice-a-day Dosage)

Approved
Approval ID

b644426c-c8ba-4fe0-80c7-d9b2dde37395

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Aug 13, 2025

Manufacturers
FDA

A-S Medication Solutions

DUNS: 830016429

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Nitrofurantoin (monohydrate/macrocrystals)

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code50090-6769
Application NumberANDA077066
Product Classification
M
Marketing Category
C73584
G
Generic Name
Nitrofurantoin (monohydrate/macrocrystals)
Product Specifications
Route of AdministrationORAL
Effective DateAugust 13, 2025
FDA Product Classification

INGREDIENTS (23)

NITROFURANTOINActive
Quantity: 25 mg in 1 1
Code: 927AH8112L
Classification: ACTIB
CARBOMER HOMOPOLYMER TYPE B (ALLYL SUCROSE CROSSLINKED)Inactive
Code: Z135WT9208
Classification: IACT
FD&C BLUE NO. 1Inactive
Code: H3R47K3TBD
Classification: IACT
FD&C RED NO. 40Inactive
Code: WZB9127XOA
Classification: IACT
GELATIN, UNSPECIFIEDInactive
Code: 2G86QN327L
Classification: IACT
LACTOSE MONOHYDRATEInactive
Code: EWQ57Q8I5X
Classification: IACT
D&C YELLOW NO. 10Inactive
Code: 35SW5USQ3G
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
POVIDONE, UNSPECIFIEDInactive
Code: FZ989GH94E
Classification: IACT
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
STARCH, CORNInactive
Code: O8232NY3SJ
Classification: IACT
TALCInactive
Code: 7SEV7J4R1U
Classification: IACT
TITANIUM DIOXIDEInactive
Code: 15FIX9V2JP
Classification: IACT
SUCROSEInactive
Code: C151H8M554
Classification: IACT
NITROFURANTOIN MONOHYDRATEActive
Quantity: 75 mg in 1 1
Code: E1QI2CQQ1I
Classification: ACTIM
KI203Inactive
Code: 35SW5USQ3G
Classification: IACT
CI 42090Inactive
Code: H3R47K3TBD
Classification: IACT
RED 40Inactive
Code: WZB9127XOA
Classification: IACT
GELATINInactive
Code: 2G86QN327L
Classification: IACT
POVIDONEInactive
Code: FZ989GH94E
Classification: IACT
SILICAInactive
Code: ETJ7Z6XBU4
Classification: IACT
ZEA MAYS (CORN) STARCHInactive
Code: O8232NY3SJ
Classification: IACT
CARBOMER 934Inactive
Code: Z135WT9208
Classification: IACT

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 8/13/2025

NITROFURANTOIN- MONOHYDRATE/MACROCRYSTALS

Label Image

HOW SUPPLIED SECTION

LOINC: 34069-5Updated: 8/13/2025

HOW SUPPLIED

Product: 50090-6769

DESCRIPTION SECTION

LOINC: 34089-3Updated: 5/10/2018

DESCRIPTION

Nitrofurantoin is an antibacterial agent specific for urinary tract infections. Nitrofurantoin capsules, USP (monohydrate/macrocrystals) are hard gelatin capsule shells containing the equivalent of 100 mg of nitrofurantoin in the form of 25 mg of nitrofurantoin macrocrystals USP and 75 mg of nitrofurantoin monohydrate USP.

The chemical name of nitrofurantoin macrocrystals USP is 1-[[[5-nitro-2-furanyl]methylene]amino]-2,4-imidazolidinedione. The chemical structure is the following:

Chemical Structure 1

Molecular Weight: 238.16

The chemical name of nitrofurantoin monohydrate USP is 1-[[[5-nitro-2-furanyl]methylene]amino]-2,4-imidazolidinedione monohydrate. The chemical structure is the following:

Chemical Structure 2

Molecular Weight: 256.17

Inactive Ingredients

Each capsule contains carbomer 934P, colloidal silicon dioxide, corn starch, compressible sugar, D&C yellow No. 10, edible white ink, FD&C blue No. 1, FD&C red No. 40, gelatin, lactose monohydrate, magnesium stearate, povidone, talc, and titanium dioxide.

Meets USP Dissolution Test 5

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Nitrofurantoin - FDA Drug Approval Details