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BUTALBITAL AND ACETAMINOPHEN

Butalbital and Acetaminophen Tablets, 50 mg/325 mg and 50 mg/300 mg Rx only

Approved
Approval ID

0a8a6a16-b23f-45d2-b5d4-540264e74d14

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Dec 15, 2022

Manufacturers
FDA

Burel Pharmaceuticals, LLC

DUNS: 609436204

Products 2

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

butalbital and acetaminophen

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code35573-455
Application NumberANDA214088
Product Classification
M
Marketing Category
C73584
G
Generic Name
butalbital and acetaminophen
Product Specifications
Route of AdministrationORAL
Effective DateDecember 15, 2022
FDA Product Classification

INGREDIENTS (10)

SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
CELLULOSE, MICROCRYSTALLINEInactive
Code: OP1R32D61U
Classification: IACT
BUTALBITALActive
Quantity: 50 mg in 1 1
Code: KHS0AZ4JVK
Classification: ACTIB
ACETAMINOPHENActive
Quantity: 300 mg in 1 1
Code: 362O9ITL9D
Classification: ACTIB
CROSCARMELLOSE SODIUMInactive
Code: M28OL1HH48
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
STARCH, CORNInactive
Code: O8232NY3SJ
Classification: IACT
POVIDONEInactive
Code: FZ989GH94E
Classification: IACT
CROSPOVIDONEInactive
Code: 2S7830E561
Classification: IACT
STEARIC ACIDInactive
Code: 4ELV7Z65AP
Classification: IACT

butalbital and acetaminophen

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code35573-456
Application NumberANDA214088
Product Classification
M
Marketing Category
C73584
G
Generic Name
butalbital and acetaminophen
Product Specifications
Route of AdministrationORAL
Effective DateDecember 15, 2022
FDA Product Classification

INGREDIENTS (10)

BUTALBITALActive
Quantity: 50 mg in 1 1
Code: KHS0AZ4JVK
Classification: ACTIB
ACETAMINOPHENActive
Quantity: 325 mg in 1 1
Code: 362O9ITL9D
Classification: ACTIB
CELLULOSE, MICROCRYSTALLINEInactive
Code: OP1R32D61U
Classification: IACT
SILICON DIOXIDEInactive
Code: ETJ7Z6XBU4
Classification: IACT
CROSCARMELLOSE SODIUMInactive
Code: M28OL1HH48
Classification: IACT
STARCH, CORNInactive
Code: O8232NY3SJ
Classification: IACT
MAGNESIUM STEARATEInactive
Code: 70097M6I30
Classification: IACT
POVIDONEInactive
Code: FZ989GH94E
Classification: IACT
CROSPOVIDONEInactive
Code: 2S7830E561
Classification: IACT
STEARIC ACIDInactive
Code: 4ELV7Z65AP
Classification: IACT

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 11/1/2022

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

NDC: 35573-455-02

Butalbital and Acetaminophen Tablets

50 mg / 300 mg

100 Tablets

Rx only

50-300

NDC: 35573-456-02

Butalbital and Acetaminophen Tablets

50 mg / 325 mg

100 Tablets

Rx only

50-325

DESCRIPTION SECTION

LOINC: 34089-3Updated: 11/1/2022

DESCRIPTION

Each Butalbital and acetaminophen tablets, 50 mg/ 325 mg for oral administration contains:

*Butalbital, USP………...….. 50 mg

Acetaminophen, USP..……. 325 mg

Each Butalbital and acetaminophen tablets, 50 mg/ 300 mg for oral administration contains:

*Butalbital, USP………...….. 50 mg

Acetaminophen, USP..……. 300 mg

  • Habit forming ingredient

In addition, each tablet contains the following inactive ingredients: Microcrystalline Cellulose, Silicified Microcrystalline Cellulose, Croscarmellose Sodium, Colloidal Silicon Dioxide, Magnesium Stearate, Pregelatinized Starch, Povidone, Crospovidone and Stearic Acid.

Butalbital (5-allyl-5-isobutylbarbituric acid), a slightly bitter, white, odorless, crystalline powder, is a short to intermediate-acting barbiturate. It has the following structural formula:

Image

C11H16N2O3 M.W.=224.26

Acetaminophen (4'-hydroxyacetanilide), a slightly bitter, white, odorless, crystalline powder, is a non- opiate, non-salicylate analgesic and antipyretic. It has the following structural formula:

Image

C8H9NO2 M.W.=151.16

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BUTALBITAL AND ACETAMINOPHEN - FDA Drug Approval Details