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DIPHENHYDRAMINE HYDROCHLORIDE

Diphenhydramine Hydrochloride Capsules USP 50 mg (Dye-free)

Approved
Approval ID

3b1ea33b-8460-31cf-e063-6394a90a5534

Product Type

HUMAN OTC DRUG LABEL

Effective Date

Jul 30, 2025

Manufacturers
FDA

Prodose, Inc.

DUNS: 119371190

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

DIPHENHYDRAMINE HYDROCHLORIDE

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code68210-5057
Application NumberM010
Product Classification
M
Marketing Category
C200263
G
Generic Name
DIPHENHYDRAMINE HYDROCHLORIDE
Product Specifications
Route of AdministrationORAL
Effective DateJuly 30, 2025
FDA Product Classification

INGREDIENTS (8)

POLYETHYLENE GLYCOL 600Inactive
Code: NL4J9F21N9
Classification: IACT
PROPYLENE GLYCOLInactive
Code: 6DC9Q167V3
Classification: IACT
GELATINInactive
Code: 2G86QN327L
Classification: IACT
WATERInactive
Code: 059QF0KO0R
Classification: IACT
POLYETHYLENE GLYCOL 400Inactive
Code: B697894SGQ
Classification: IACT
SORBITOLInactive
Code: 506T60A25R
Classification: IACT
GLYCERINInactive
Code: PDC6A3C0OX
Classification: IACT
DIPHENHYDRAMINE HYDROCHLORIDEActive
Quantity: 50 mg in 1 1
Code: TC2D6JAD40
Classification: ACTIB

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 7/30/2025

Bulk Package Label

Bulk Label

INDICATIONS & USAGE SECTION

LOINC: 34067-9Updated: 7/30/2025

Uses

  • for relief of occasional sleeplessness

OTC - ASK DOCTOR/PHARMACIST SECTION

LOINC: 50568-5Updated: 7/30/2025

Ask a doctor or pharmacist before use if you are

taking sedatives or tranquilizers

OTC - WHEN USING SECTION

LOINC: 50567-7Updated: 7/30/2025

When using this product

avoid alcoholic drinks

OTC - STOP USE SECTION

LOINC: 50566-9Updated: 7/30/2025

Stop use and ask a doctor if

sleeplessness persist continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

LOINC: 50565-1Updated: 4/8/2025

Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away.

OTC - PREGNANCY OR BREAST FEEDING SECTION

LOINC: 53414-9Updated: 7/30/2025

If pregnant or breast-feeding,

ask a health professional before use.

DOSAGE & ADMINISTRATION SECTION

LOINC: 34068-7Updated: 7/30/2025

Directions

  • adults and children 12 years of age and over: 1 softgel (50 mg) at bedtime if needed, or as directed by a doctor

INACTIVE INGREDIENT SECTION

LOINC: 51727-6Updated: 7/30/2025

Inactive ingredients

gelatin, glycerin, polyethylene glycol 400, polyethylene glycol 600, propylene glycol, purified water, sorbitol sorbitan solution.

OTC - ACTIVE INGREDIENT SECTION

LOINC: 55106-9Updated: 7/30/2025

Active ingredient

(in each softgel)

Diphenhydramine Hydrochloride USP 50 mg

OTC - PURPOSE SECTION

LOINC: 55105-1Updated: 7/30/2025

Purpose

Nighttime sleep-aid

WARNINGS SECTION

LOINC: 34071-1Updated: 7/30/2025

Warnings

Do not use

  • for children under 12 years of age
  • with any other product containing diphenhydramine, even one used on skin

OTC - ASK DOCTOR SECTION

LOINC: 50569-3Updated: 7/30/2025

Ask a doctor before use if you have

  • a breathing problem such as emphysema or chronic bronchitis
  • glaucoma
  • trouble urinating due to an enlarged prostate gland

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DIPHENHYDRAMINE HYDROCHLORIDE - FDA Drug Approval Details