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Nystatin

NYSTATIN OINTMENT USP (100,000 units/g)

Approved
Approval ID

d7d04c02-d07d-4382-8f93-5c0c3e68790c

Product Type

HUMAN PRESCRIPTION DRUG LABEL

Effective Date

Oct 1, 2022

Manufacturers
FDA

Proficient Rx LP

DUNS: 079196022

Products 1

Detailed information about drug products covered under this FDA approval, including NDC codes, dosage forms, ingredients, and administration routes.

Nystatin

Product Details

FDA regulatory identification and product classification information

FDA Identifiers
NDC Product Code63187-464
Application NumberANDA062840
Product Classification
M
Marketing Category
C73584
G
Generic Name
Nystatin
Product Specifications
Route of AdministrationTOPICAL
Effective DateOctober 1, 2022
FDA Product Classification

INGREDIENTS (2)

PETROLATUMInactive
Code: 4T6H12BN9U
Classification: IACT
NYSTATINActive
Quantity: 100000 [USP'U] in 1 g
Code: BDF1O1C72E
Classification: ACTIB

Drug Labeling Information

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

LOINC: 51945-4Updated: 10/1/2022

Package/Label Display Panel

63187-464-15

INDICATIONS & USAGE SECTION

LOINC: 34067-9Updated: 10/1/2022

INDICATIONS AND USAGE

Nystatin Ointment USP is indicated in the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida (Monilia) albicans and other Candida species.

CONTRAINDICATIONS SECTION

LOINC: 34070-3Updated: 10/1/2022

CONTRAINDICATIONS

Nystatin Ointment USP is contraindicated in patients with a history of hypersensitivity to any of its components.

ADVERSE REACTIONS SECTION

LOINC: 34084-4Updated: 10/1/2022

ADVERSE REACTIONS

Nystatin is virtually nontoxic and nonsensitizing and is well tolerated by all age groups including debilitated infants, even on prolonged administration.

If irritation on topical application should occur, discontinue medication.

SPL UNCLASSIFIED SECTION

LOINC: 42229-5Updated: 10/1/2022

Rx Only

DESCRIPTION SECTION

LOINC: 34089-3Updated: 10/1/2022

DESCRIPTION

Each gram of Nystatin Ointment USP contains 100,000 units of nystatin in a white petrolatum base.

CLINICAL PHARMACOLOGY SECTION

LOINC: 34090-1Updated: 10/1/2022

CLINICAL PHARMACOLOGY

Nystatin is an antifungal antibiotic which is both fungistatic and fungicidal in vitro, against a wide variety of yeasts and yeast-like fungi. It probably acts by binding to sterols in the cell membrane of the fungus with a resultant change in membrane permeability allowing leakage of intracellular components. Nystatin is a polyene antibiotic of undetermined structural formula that is obtained from Streptomyces noursei, and is the first well tolerated antifungal antibiotic of dependable efficacy for the treatment of cutaneous, oral and intestinal infections caused by Candida (Monilia) albicans and other Candida species. It exhibits no appreciable activity against bacteria.

Nystatin provides specific therapy for all localized forms of candidiasis. Symptomatic relief is rapid, often occurring within 24 to 72 hours after the initiation of treatment. Cure is effected both clinically and mycologically in most cases of localized candidiasis.

PRECAUTIONS SECTION

LOINC: 42232-9Updated: 10/1/2022

PRECAUTIONS

Should a reaction of hypersensitivity occur the drug should be immediately withdrawn and appropriate measures taken.

DOSAGE & ADMINISTRATION SECTION

LOINC: 34068-7Updated: 10/1/2022

DOSAGE AND ADMINISTRATION

Nystatin Ointment USP should be applied liberally to the affected areas twice a day or as indicated until healing is complete. The ointment does not stain the skin or mucous membranes and it provides a simple, convenient means of treatment.

HOW SUPPLIED SECTION

LOINC: 34069-5Updated: 10/1/2022

HOW SUPPLIED

Nystatin Ointment USP 100,000 units/g

15 g tube (0**.**53 oz)

Store at controlled room temperature 15°-30°C (59°-86°F). Do not freeze.

Distributed by:

Actavis Pharma, Inc.

Parsippany, NJ 07054 USA

FORM NO. 0166

Rev. 10/19

VC2752

Relabeled By:

Proficient Rx LP

Thousand Oaks, CA 91320

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Nystatin - FDA Drug Approval Details