TOBREX STERILE OPHTHALMIC OINTMENT 0.3%

OINTMENT

**4.2 Posology and method of administration** **Posology** As indicated by physician: In mild to moderate disease, apply a 1.5 centimetre ribbon into the affected eye(s) 2 or 3 times per day. In severe infections, instill a 1.5 centimetre ribbon into the eye(s) every 3 to 4 hours until improvement, following which treatment should be reduced prior to discontinuation. Tobrex ophthalmic ointment may be used in conjunction with Tobrex ophthalmic solution. Use in children The safety and efficacy of Tobrex® Ophthalmic Ointment in children younger than 1 year of age have not been established. Use in patients with hepatic or renal impairment The safety and efficacy of Tobrex® Ophthalmic Ointment in patients with hepatic or renal impairment have not been established. Use in elderly population No overall clinical differences in safety or efficacy have been observed between the elderly and other adult populations. **Method of administration** For ocular use. To avoid contamination, the tube tip should not touch any surface. The tube tip should also not come into contact with the eye as this may cause injury to the eye. Keep the tube tightly closed when not in use. Either nasolacrimal occlusion or gently closing the eyelid(s) after administration is recommended. This may reduce the systemic absorption of medicinal products administered via the ocular route and result in a decrease in systemic adverse reactions. If more than one topical ophthalmic product is being used, the products must be administered at least 5 minutes apart. Eye ointments should be administered last.