- Approval Id
- 1d653bf9b06c97b1
- Drug Name
- PMS-CHOLESTYRAMINE POWDER
- Product Name
- PMS-CHOLESTYRAMINE POWDER
- Approval Number
- SIN07426P
- Approval Date
- 1993-05-12
- Registrant
- SYNMOSA BIOPHARMA PTE. LTD.
- Licence Holder
- SYNMOSA BIOPHARMA PTE. LTD.
- Drug Type
- Therapeutic
- Forensic Classification
- PRESCRIPTION ONLY MEDICINES
- Dosage Form
- POWDER
- Dosage
- <p><strong>DOSAGE AND ADMINISTRATION</strong><br>
Cholestyramine resin is administered orally. To avoid oesophageal irritation or blockage or intestinal blockage, the drug should not be taken in its dry form. pms-Cholestyramine Powder should always be mixed with an appropriate fluid prior to ingestion (see Preparation – <em>please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information</em>).<br>
To minimize gastrointestinal side effects and to familiarize the patient with pms-Cholestyramine, therapy should be initiated with one dose of pms-Chotestyramine Powder daily. After one to two days the dosage can be increased to meet the patient's needs.<br>
The usual initial adult dosage of cholestyramine resin is 4 grams one to six times daily. Subsequent dosage should be adjusted according to the patient's requirements and response.<br>
A pediatric dosage schedule has not been established.</p>
- Route Of Administration
- ORAL
- Indication Info
- <p><strong>INDICATIONS</strong><br>
Cholestyramine resin is indicated as an adjunct to dietary therapy and exercise to decrease elevated serum cholesterol in the management of primary type IIa and type IIb hypercholesterolemia (elevated low density lipoprotein) and to reduce the risks of antherosclerotic coronary artery disease and myocardial infarction. Although cholestyramine may also lower plasma cholesterol concentration in patients with other types of hyperlipoproteinemia, the drug may increase plasma triglyceride concentrations and, therefore, should not be used alone in patients with hyperlipidemias associated with hypertriglyceridemia.<br>
Cholestyramine resin is indicated as a symptomatic control of diarrhea caused by increased bile acids due to short bowel syndrome.</p>
<p>Cholestyramine resin is indicated for the relief of pruritus associated with partial biliary obstruction.</p>
- Contraindications
- <p><strong>CONTRAINDICATIONS</strong><br>
Cholestyramine resin is contraindicated in patients with complete biliary obstruction in which no bile products reach the intestine.<br>
It is also contraindicated in patients who are hypersensitive to the drug or to any ingredient in its formulation.<br>
Pms-Cholestyramine resin should not be taken in its dry form. Cholestyramine may delay or reduce absorption of other medications administered concurrently because of its anion-binding activity; administration of other medications 1 hour before or 4 to 6 hours after cholestyramine is recommended, although absorption of some medications is impaired even then.</p>
- Atc Code
- C10AC01
- Atc Item Name
- colestyramine
- Pharma Manufacturer Name
- MEDICELL PHARMACEUTICAL (S) PTE. LTD.
- Company Detail Path
- /organization/medicell-pharmaceutical-s-pte-ltd
