- Approval Id
- 284df33d9f569abf
- Drug Name
- STREPTOMYCIN SULFATE FOR INJECTION 1 G/VIAL
- Product Name
- STREPTOMYCIN SULFATE FOR INJECTION 1 G/VIAL
- Approval Number
- SIN01388P
- Approval Date
- 1988-05-19
- Registrant
- PHARMAZEN MEDICALS PTE LTD
- Licence Holder
- PHARMAZEN MEDICALS PTE LTD
- Drug Type
- Therapeutic
- Forensic Classification
- PRESCRIPTION ONLY MEDICINES
- Dosage Form
- INJECTION, POWDER, FOR SOLUTION
- Dosage
- <p><strong>DOSAGE</strong></p>
<p><strong>Treatment of tuberculosis :</strong><br>
15 mg/kg BW (maximum 1 g) given once daily for 5 days in a week or 25 – 30 mg/kg BW given twice daily.</p>
<p><strong>Treatment of tularemia :</strong><br>
One to 2 g daily in divided doses for 7 to 14 days until the patient is afebrile for 5 to 7 days.</p>
<p><strong>Treatment of endocarditis :</strong></p>
<ol type="a">
<li><em>Streptococcal endocarditis</em>; in penicillin-sensitive alpha and non-hemolytic Streptococcal endocarditis (penicillin MIC ≤ 0.1 mcg/mL), streptomycin may be used for 2-week treatment concomitantly with penicillin. The streptomycin regimen is 1 g b.i.d. for the first week, and 500 mg b.i.d. for the second week. If the patient is over 60 years age, the dosage should be 500 mg b.i.d. for the entire 2-week period.</li>
<li><em>Enterococcal endocarditis</em>: Streptomycin in doses of 1 g b.i.d. for 2 weeks and 500 mg b.i.d. for an additional 4 weeks is given in combination with penicillin. Ototoxicity may require termination of the streptomycin prior to completion of the 6-week course of treatment.</li>
</ol>
<p><strong>Treatment of chancroid, urinary tract infections, meningitis and pneumonia :</strong><br>
1 to 2 grams in divided doses every six to twelve hours for moderate to severe infections. Doses should generally not exceed 2 grams per day.</p>
- Route Of Administration
- INTRAMUSCULAR
- Indication Info
- <p><strong>INDICATIONS</strong></p>
<ol>
<li>Treatment of Tuberculosis in conjunction with other anti-tuberculosis agents</li>
<li>Treatment of tularemia</li>
<li>Treatment of chancroid</li>
<li>Treatment of urinary tract infections, respiratory tract infections, meningitis, endocarditis and pneumonia which are caused by microorganisms which have shown to be susceptible to the antibacterial effects of streptomycin</li>
</ol>
- Contraindications
- <p><strong>CONTRAINDICATIONS</strong></p>
<ol>
<li>Hypersensitive of this drugs or another aminoglycoside that caused by the cross sensitivity</li>
<li>Hearing disturbance</li>
<li>Myasthenia gravis</li>
<li>Pregnancy</li>
</ol>
- Atc Code
- J01GA01
- Atc Item Name
- streptomycin
- Pharma Manufacturer Name
- PHARMAZEN MEDICALS PTE LTD
