- Approval Id
- 2f5c1467ed99d3e5
- Drug Name
- HERBESSER FOR INJECTION 10 mg/ampoule
- Product Name
- HERBESSER FOR INJECTION 10 mg/ampoule
- Approval Number
- SIN06013P
- Approval Date
- 1991-06-05
- Registrant
- PHARMAFORTE SINGAPORE PTE LTD
- Licence Holder
- PHARMAFORTE SINGAPORE PTE LTD
- Drug Type
- Therapeutic
- Forensic Classification
- Prescription Only
- Dosage Form
- INJECTION, POWDER, FOR SOLUTION
- Dosage
- <p><strong>DOSAGE AND ADMINISTRATION</strong><br>
The drug (10 mg or 50 mg as diltiazem hydrochloride) is dissolved in at least 5 ml of physiological saline or glucose solution for injection before use and administered as follows:</p>
<ul>
<li>Tachyarrhythmia (supraventricular)<br> Usually for adults, 10 mg of diltiazem hydrochloride as a single dosage is intravenously injected slowly for about 3 minutes. The dosage may be adjusted depending on the patient's age and symptoms.</li>
<li>Emergency treatment for abnormal hypertension during operation<br>
Intravenous bolus injection:<br>
Usually for adults, 10 mg of diltiazem hydrochloride as a single dosage is intravenously injected slowly for about one minute. The dosage may be adjusted depending on the patient's age and symptoms.<br>
Intravenous drip infusion:<br>
Usually for adults, 5 to 15 mcg of diltiazem hydrochloride/kg body weight per minute is intravenously injected in drip infusion. After blood pressure is lowered to the target level, adjust the drip infusion rate while monitoring blood pressure.</li>
<li>Hypertensive emergency<br>
Usually for adults, 5 to 15 mcg of diltiazem hydrochloride/kg body weight per minute is intravenously injected in drip infusion. After blood pressure is lowered to the target level, adjust the drip infusion rate while monitoring blood pressure.</li>
<li>Unstable angina<br>
Usually for adults, 1 to 5 mcg of diltiazem hydrochloride/kg body weight per minute is intravenously injected in drip infusion.<br>
The dosage should be started with a low dose and may be adjusted depending on the patient's symptoms. The maximum dosage should be 5 mcg of diltiazem hydrochloride/kg body weight per minute.</li>
</ul>
- Route Of Administration
- INTRAVENOUS
- Indication Info
- <p><strong>INDICATIONS</strong></p>
<ul>
<li>Tachyarrhythmia (supraventricular)</li>
<li>Emergency treatment for abnormal hypertension during operation</li>
<li>Hypertensive emergency</li>
<li>Unstable angina</li>
</ul>
- Contraindications
- <p><strong>CONTRAINDICATIONS (HERBESSER Injection is contraindicated in the following patients.)</strong></p>
<ol class="decimalparen">
<li>Patients with severe hypotension or cardiogenic shock [The symptoms may be exacerbated.]</li>
<li>Patients with 2nd or more degree atrioventricular block or sick sinus syndrome (continuous sinus bradycardia less than 50 beats/ minute, sinus arrest, sinoatrial block, etc.) [Excessively inhibitory effect of the drug on cardiac stimulus-formation and conduction may occur.]</li>
<li>Patients with severe congestive heart failure [The symptoms of heart failure may be exacerbated.]</li>
<li>Patients with severe cardiomyopathy [The symptoms of heart failure may be exacerbated.]</li>
<li>Patients with a history of hypersensitivity to any of the ingredients in the drug</li>
<li>Pregnant women or women who may possibly be pregnant [See PRECAUTIONS -Use during Pregnancy, Delivery or Lactation – <em>please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information</em>.]</li>
</ol>
- Atc Code
- C08DB01
- Atc Item Name
- diltiazem
- Pharma Manufacturer Name
- PHARMAFORTE SINGAPORE PTE LTD
