COLPERMIN CAPSULE 187mg

**What is Colpermin® and how is it used?** The active constituent of Colpermin is natural peppermint oil, which is obtained from the overground parts of Mentha Piperita L (peppermint). Colpermin capsules contain peppermint oil, with its chief constituent, menthol, embedded in a paste-like base. Colpermin has a relaxing, antispasmodic effect on the bowel muscles in hyperirritability of the bowel, especially of the large bowel (irritable colon), and in bowel spasm, particularly large-bowel spasm. The relaxing effect of peppermint oil prevents unpleasant sensation of fullness and bloating, and facilitates the passing of bowel gases. Accompanying cramp-like pains are thus relieved. In order for the peppermint oil to be able to take effect locally in the bowel, cach capsule is coated with a gastric acid-resistant protective film, which prevents premature release of the peppermint oil in the stomach. Colpermin is intended for the relief of symptoms of irritable bowel syndrome.

**When must Colpermin® not be used at all or only with caution?** Colpermin must not be used in cases of known hypersensitivity to peppermint oil, especially menthol, or to any of the excipients listed in the composition. Colpermin should not be used in cases of bile duct obstruction, gallbladder inflammation or liver damage. In adolescents or children under 15 years of age, Colpermin should be administered only if expressly prescribed by a doctor. Administration at the same time as products for heartburn or when there is a deficiency of hydrochloric acid in the stomach should be avoided. Please tell your doctor or pharmacist if you - have any other illnesses - have allergies - are taking other medicinal products (including over-the-counter ones). Please consult a doctor before use if it is the first presentation of symptoms for confirmation of irritable bowel syndrome.

WELLCHEM PHARMACEUTICALS PTE LTD

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